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267731

Pyrimidines as Anticancer and Antiviral: Synthesis & Reactions (A Review)

Article

Last updated: 22 Jan 2023

OverviewSimilar Items

Subjects

-

Tags

Section B: Pharmaceutical Analytical & Organic Chemistry, Medicinal & Biochemistry

Abstract

Background: The interest of many medicinal and organic chemists has been attracted to the synthesis of pyrimidines and their analogues due to their highly biological and medicinal properties. Objectives& Methodology: Based on these activities, this review discusses the various recent methods for the synthesis of these heterocyclic compounds during the period of 2017 to 2021 with certain two main medicinal actions. Conclusion: Pyrimidine moiety bearing compounds, are synthesized, and reacted either through one-pot synthesis or multi-step synthesis pathways, in catalytic and solvent free condition or using catalysts and solvent.

DOI

10.21608/aprh.2022.144745.1180

Keywords

pyrimidines, Anticancer, Antiviral, Reactions, Synthesis

Authors

First Name

Samar

Last Name

Fatahala

MiddleName

-

Affiliation

Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Helwan University, Helwan, Cairo,11795, Egypt

Email

samarradwan1@yahoo.com

City

cairo

Orcid

-

First Name

Mosaad

Last Name

Mohamed

MiddleName

-

Affiliation

Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Helwan University, Helwan, Cairo,11795, Egypt

Email

doctormosaad@hotmail.com

City

Cairo

Orcid

-

First Name

Marwa

Last Name

Khodair

MiddleName

-

Affiliation

Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Helwan University, Helwan, Cairo,11795, Egypt

Email

marwokhodair13@gmail.com

City

cairo

Orcid

0000-0002-9954-140X

First Name

Rania

Last Name

Abd El-Hameed

MiddleName

-

Affiliation

Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Helwan University, Helwan, Cairo,11795, Egypt

Email

zeiadomar@yahoo.com

City

Cairo

Orcid

-

Volume

6

Article Issue

4

Related Issue

37446

Issue Date

2022-10-01

Receive Date

2022-06-14

Publish Date

2022-10-01

Page Start

155

Page End

180

Print ISSN

2357-0547

Online ISSN

2357-0539

Article File

APRH_Volume 6_Issue 4_Pages 155-180.pdf

PDF . 885.7kB

Link

https://aprh.journals.ekb.eg/article_267731.html

Detail API

https://aprh.journals.ekb.eg/service?article_code=267731

Order

1

Type

Review Article

Type Code

358

Publication Type

Journal

Publication Title

Journal of Advanced Pharmacy Research

Publication Link

https://aprh.journals.ekb.eg/

MainTitle

-

Details

Type

Article

Created At

22 Jan 2023