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216007

COVID-19 Vaccination During Gestation and Lactation: Leaps in Comprehension

Article

Last updated: 03 Jan 2025

Subjects

-

Tags

Section E: Microbiology & Immunology

Abstract

Introduction: A total of 7.3 billion vaccine doses of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been administered globally up to 19 November 2021. Yet, in the paucity of evidence regarding effectiveness and safety among special populations, the concern of undergoing vaccination during gestation and breastfeeding is a matter of considerable regional and global dilemma. However, herd immunity remains the only effective COVID-19 prevention strategy, which entails vaccinating gestational as well as breastfeeding females. Methods: We, therefore, present an up-to-date literature review of the most recent evidence and information using multiple research engines, including PubMed and Google Scholar, as well as ClinicalTrials.gov. Objectives: To retrieve concrete proof to aid in making an evidence-based approach towards maternal immunization. Results: The results showed growing evidence of benefit and insufficient proof of harm from several studies that enrolled gestational and lactating females. Studies also reported that gestational and breastfeeding participants mount a fairly similar initial serological response to that encountered in non-pregnant counterparts. Conclusion: It is strongly recommended to keep assessing clinical trials, observational studies, and all possible available findings to broaden our perception regarding vaccination in gestational and lactating females.

DOI

10.21608/aprh.2021.104588.1145

Keywords

COVID-19 vaccine, gestation, lactation

Authors

First Name

E. Salem

Last Name

Fatma

MiddleName

-

Affiliation

Department of Microbiology and Immunology, Faculty of Pharmacy, Helwan University, Ain-Helwan, Cairo 11795, Egypt

Email

fatma.salem@pharm.helwan.edu.eg

City

-

Orcid

-

First Name

Ali

Last Name

Shima Mahmoud

MiddleName

-

Affiliation

Department of Microbiology and Immunology, Faculty of Pharmacy, Helwan University, Ain-Helwan, Cairo 11795, Egypt

Email

shaima.mn@gmail.com

City

-

Orcid

-

First Name

Aboulwafa

Last Name

Mohammad M.

MiddleName

-

Affiliation

Department of Microbiology and Immunology, Faculty of Pharmacy, Ain Shams University, Organization of African Unity St., Abbassia, POB: 11566, Cairo, Egypt , Faculty of Pharmacy, King Salman International University, Ras Sudr, South Sinai, Egypt

Email

maboulwafa@pharma.asu.edu.eg

City

-

Orcid

-

First Name

M. Shawky

Last Name

Riham

MiddleName

-

Affiliation

Department of Microbiology and Immunology, Faculty of Pharmacy, Helwan University, Ain-Helwan, Cairo 11795, Egypt

Email

shawky.riham@gmail.com

City

Cairo

Orcid

-

Volume

6

Article Issue

1

Related Issue

30533

Issue Date

2022-01-01

Receive Date

2021-11-06

Publish Date

2022-01-01

Page Start

34

Page End

45

Print ISSN

2357-0547

Online ISSN

2357-0539

Link

https://aprh.journals.ekb.eg/article_216007.html

Detail API

https://aprh.journals.ekb.eg/service?article_code=216007

Order

5

Type

Review Article

Type Code

358

Publication Type

Journal

Publication Title

Journal of Advanced Pharmacy Research

Publication Link

https://aprh.journals.ekb.eg/

MainTitle

COVID-19 Vaccination During Gestation and Lactation: Leaps in Comprehension

Details

Type

Article

Created At

22 Jan 2023