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26346

A Comprehensive Review on Genus Zygophyllum

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Last updated: 22 Jan 2023

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Abstract

Objectives: This study aimed to make a broad review of the chemical constituents and biological activities of genus Zygophyllum. Methods: This review covers the peer reviewed articles between 1977 and August, 2018, retrieved from PubMed, Science Direct, Sci-Hub, Springer and Wikipedia Results: In traditional medicine, plants of genus Zygophyllum have been employed and utilized as anti-rheumatic, anti-gout, antidiabetic, anti-hyperlipidemic, antimicrobial, anti-oxidant, antihypertensive, antiseptic, anti-eczema and antidiarrheal. Zygophyllum species have been phytochemically studied leading to the identification of various classes of compounds including triterpenes, flavonoids, saponins, sterols, simple phenolic compounds, and esters. Biological studies on Zygophyllum species have also indicated various bioactive potentials including antioxidant, antidiabetic, antimicrobial antitumor and anti-inflammatory effects. The reported medicinal Zygophyllum species were selected and summarized on basis of their; geographical distribution, traditional uses, chemical constituents and biological activities. Conclusion: It would therefore be important to extensively investigate their phytochemicals and pharmacologically determine their activities for future drug discovery and development.

DOI

10.21608/aprh.2019.5699.1066

Keywords

Zygophyllum, Geographical distribution, Traditional uses, chemical constituents, biological activities

Authors

First Name

Enas

Last Name

Shawky

MiddleName

-

Affiliation

Pharmacognosy Department, Faculty of Pharmacy, Egyptian Russian University, Cairo, Egypt.

Email

enasmenasm@yahoo.com

City

Cairo

Orcid

-

First Name

Nagwan

Last Name

Gabr

MiddleName

-

Affiliation

Pharmacognosy Department, Faculty of Pharmacy, Helwan University.

Email

nagnag181980@yahoo.com

City

-

Orcid

-

First Name

Mohamed

Last Name

El-gindi

MiddleName

-

Affiliation

Pharmacognosy Department, Faculty of Pharmacy, Helwan University.

Email

mohamed_ahmed04@pharm.helwan.edu.eg

City

Cairo

Orcid

0000-0002-8588-9456

First Name

Reham

Last Name

Mekky

MiddleName

-

Affiliation

Pharmacognosy Department, Faculty of Pharmacy, Egyptian Russian University, Cairo, Egypt.

Email

reham.hassan@gmail.com

City

Cairo

Orcid

-

Volume

3

Article Issue

1

Related Issue

4745

Issue Date

2019-01-01

Receive Date

2018-10-16

Publish Date

2019-01-01

Page Start

1

Page End

16

Print ISSN

2357-0547

Online ISSN

2357-0539

Article File

APRH_Volume 3_Issue 1_Pages 1-16.pdf

PDF . 853.8kB

Link

https://aprh.journals.ekb.eg/article_26346.html

Detail API

https://aprh.journals.ekb.eg/service?article_code=26346

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Review Article

Type Code

358

Publication Type

Journal

Publication Title

Journal of Advanced Pharmacy Research

Publication Link

https://aprh.journals.ekb.eg/

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Article

Created At

22 Jan 2023