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Evaluation of Parenteral Antioxidant as a Protective Therapy Against Electromagnetic Radiation Produced by Cell Phones on Hematological and Biochemical Parameters in Rats

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Last updated: 03 Jan 2025

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Abstract

Objectives: Radiofrequency of mobile phones may affect biological systems by increasing free radicals and by changing the antioxidant defense systems of tissues, thus leading to oxidative stress. L-cysteine, as a glutathione precursor, has an antioxidant property that may prevent oxidative damage to normal cellular processes. Methods: The effect of different concentrations of parentral L-CyS-HCl against harmful effects of EMR on rats' blood was studied namely: hematological parameters (osmotic fragility and blood picture), and biochemical parameters (reduced glutathione and malondialdehyde levels). Results: The results revealed that 20 mg parenteral L-CyS-HCl showed high protection for EMR radiated rats against hemolysis. In addition, EMR radiated rats received 20 mg parenteral L-CyS-HCl showed normal blood picture, GSH and Malondialdehyde levels, compared to radiated untreated rats. Conclusion:Parenteral L-CyS-HCl can be used for protection against mobile phone hazards

DOI

10.21608/aprh.2017.4833

Keywords

electromagnetic radiation (EMR), Glutathione (GSH, Mobile phone hazards, L-cysteine, Oxidative Stress

Authors

First Name

Samia

Last Name

Omar

MiddleName

-

Affiliation

Department of Pharmaceutics, Faculty of Pharmacy, Helwan University, Ain Helwan, Cairo11795, Egypt

Email

omarsamia3@hotmail.com

City

-

Orcid

-

First Name

Mohamed

Last Name

Nasr

MiddleName

-

Affiliation

Department of Pharmaceutics, Faculty of Pharmacy, Helwan University, Ain Helwan, Cairo11795, Egypt

Email

-

City

-

Orcid

-

First Name

Diana

Last Name

Rafla

MiddleName

A.

Affiliation

Department of Pharmaceutics, Faculty of Pharmacy, Helwan University, Ain Helwan, Cairo11795, Egypt

Email

diana.rafla@yahoo.com

City

-

Orcid

-

Volume

2

Article Issue

1

Related Issue

824

Issue Date

2018-01-01

Receive Date

2017-09-09

Publish Date

2018-01-01

Page Start

28

Page End

35

Print ISSN

2357-0547

Online ISSN

2357-0539

Article File

APRH_Volume 2_Issue 1_Pages 28-35.pdf

PDF . 754.7kB

Link

https://aprh.journals.ekb.eg/article_4833.html

Detail API

https://aprh.journals.ekb.eg/service?article_code=4833

Order

3

Type

Research Article

Type Code

318

Publication Type

Journal

Publication Title

Journal of Advanced Pharmacy Research

Publication Link

https://aprh.journals.ekb.eg/

MainTitle

Evaluation of Parenteral Antioxidant as a Protective Therapy Against Electromagnetic Radiation Produced by Cell Phones on Hematological and Biochemical Parameters in Rats

Details

Type

Article

Created At

22 Jan 2023