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16155

Synthesis Strategies and Biological Value of Pyrrole and Pyrrolopyrimidine

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Last updated: 22 Jan 2023

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Abstract

For several decades, interest in the synthesis pyrrole and pyrrolopyrimidine increases due to the importance of these heterocycles both from chemical and biological points of view. They possess several biological activities such as anti-microbial, analgesic, anti-inflammatory, anti-cancer, anti-viral, anti-convulsant, anti-hyperlipidemic, anti-depressant, anti-diabetic, anti-allergic activities. These findings motivated us to present this review which highlights different methods of the synthesis of pyrrole and pyrrolopyrimidine derivatives as well as their biological importance from the past to recent years.

DOI

10.21608/aprh.2017.16155

Keywords

analgesic, Anti-allergic, Anti-cancer, Anti-convulsant, anti-depressant, anti-diabetic, Anti-hyperlipidemic, Anti-inflammatory, anti-microbial, Anti-viral, 7-deazapurine, Knorr pyrrole synthesis, Paal Knorr, pyrrole, Pyrrolopyrimidine, Synthesis

Authors

First Name

Mosaad

Last Name

Mohamed

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Affiliation

Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Helwan University, Ain Helwan, Cairo, Egypt.

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First Name

Rania

Last Name

Abd El-Hameed

MiddleName

-

Affiliation

Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Helwan University, Ain Helwan, Cairo, Egypt.

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Orcid

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First Name

Amira

Last Name

Sayed

MiddleName

-

Affiliation

Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Helwan University, Ain Helwan, Cairo, Egypt.

Email

amiraelsaedy@yahoo.com

City

Helwan

Orcid

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Volume

1

Article Issue

1

Related Issue

233

Issue Date

2017-01-01

Receive Date

2016-10-23

Publish Date

2017-01-01

Page Start

1

Page End

24

Print ISSN

2357-0547

Online ISSN

2357-0539

Article File

APRH_Volume 1_Issue 1_Pages 1-24.pdf

PDF . 3.6MB

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https://aprh.journals.ekb.eg/article_16155.html

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https://aprh.journals.ekb.eg/service?article_code=16155

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Journal

Publication Title

Journal of Advanced Pharmacy Research

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https://aprh.journals.ekb.eg/

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Article

Created At

22 Jan 2023