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235257

New Derivatives from 4-Amino Anti-Pyrine and Vanillin, Synthesis Characterization and Antibacterial Activity

Article

Last updated: 01 Jan 2025

Subjects

-

Tags

Organic chemistry

Abstract

Schiff base, Azo-Schiff base, nickel (II), and copper (II) complexes have been prepared successfully from 4-amino antipyrine and vanillin and diagnosed by UV-visible, FT-IR, 1H-NMR, and 13C-NMR. The derivative compound Azo-Schiff with a 200 mg/ml concentration has good antibacterial activity with a diameter of inhibition zone 16.11 ± 0.1035 mm and 13.21 ± 0.4044 against Staphylococcus aureus (S. aureus) and Pseudomonas aeruginosa (P. aeruginosa), respectively. Therefore, this compound may be considered a raw material for manufacturing treatments against these bacterial infections.

DOI

10.21608/ejchem.2022.135727.5977

Keywords

4-Amino antipyrine, Azo schiff base, complexes, Biological Activity, S. aureus, P. aeruginosa

Authors

First Name

Hawraa

Last Name

Alabidi

MiddleName

M

Affiliation

Department of Chemistry, Faculty of Science, University of Kufa, Iraq

Email

hawraam.alabidi@uokufa.edu.iq

City

-

Orcid

-

First Name

Ali M

Last Name

Farhan

MiddleName

-

Affiliation

Ministry of Education, Al-Najaf, Iraq

Email

aliphd256@gmail.com

City

-

Orcid

-

First Name

Hutham Mahmood Yousif

Last Name

Al-labban

MiddleName

-

Affiliation

Department of Chemistry, Faculty of Science, University of Kufa, Iraq

Email

huthamm.sadiq@uokufa.edu.iq

City

kufa

Orcid

-

First Name

Ahmed Abduljabbar Jaloob

Last Name

Aljanaby

MiddleName

-

Affiliation

Department of Biology, Faculty of Science, University of Kufa, Iraq

Email

ahmedaj.aljanabi@uokufa.edu.iq

City

KUFA

Orcid

http://orcid.org/000

Volume

66

Article Issue

1

Related Issue

38521

Issue Date

2023-01-01

Receive Date

2022-04-24

Publish Date

2023-01-01

Print ISSN

0449-2285

Online ISSN

2357-0245

Link

https://ejchem.journals.ekb.eg/article_235257.html

Detail API

https://ejchem.journals.ekb.eg/service?article_code=235257

Order

235,257

Type

Original Article

Type Code

297

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry

Publication Link

https://ejchem.journals.ekb.eg/

MainTitle

New Derivatives from 4-Amino Anti-Pyrine and Vanillin, Synthesis Characterization and Antibacterial Activity

Details

Type

Article

Created At

22 Jan 2023