There are various techniques to protect and decrease the corrosion rate of carbon steel in acidic environments such as using corrosion inhibitors. Therefore, the need to search for corrosion inhibitors that have high efficiency in protecting carbon steel in different acidic media and at low costs was revealed. The inhibitive effect of various inhibitors [100 mg sodium nitrate (SN), 100 mg ceftriaxone sodium (CS), and 50 mg sodium nitrate (SN) + 50 mg ceftriaxone sodium (CS)] on the corrosion behavior of carbon steel in various acidic media (one molarity concentration (1M) of HCl, H2SO4, and HNO3 solutions) was investigated using the weight loss method. The results proved that sodium nitrate was the best inhibitor for protecting and decreasing the corrosion rate of carbon steel in a 1 M HNO3 environment but the ceftriaxone sodium was the optimum choice for reducing the corrosion behavior of carbon steel in 1 M HCl, 1 M H2SO4 solutions. The theoretical parameter (CPR) gave important assistance in understanding the corrosion inhibition behavior and mechanism and are in complete agreement with the experimental data.