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232098

Antialopecia Activity and IR-Spectrometry Characterization of Bioactive Compounds From Sansevieria trifasciata P.

Article

Last updated: 01 Jan 2025

OverviewSimilar Items

Subjects

-

Tags

Pharmaceutical Chemistry

Abstract

Androgenetic Alopecia (AGA) causes more than 90% of alopecia cases. Drugs for the treatment of AGA have toxic and side effects, so it is necessary to find new drugs from the natural product, such as Sansevieria trifasciata. This study aims to determine the hair growth activity of subfraction from Sansevieria trifasciata and characterize the isolate using infrared spectroscopy. The fraction of Sansevieria trifasciata was separated using column chromatography. The hair growth activity using the modified Tanaka method. Skin biopsies of each rabbit stained with hematoxylin and eosin. The characterization of the isolate using infrared spectroscopy (FT-IR). The separation of fractions obtained six subfractions. The hair growth activity from subfraction-C was higher with the hair growth length of 2.80 cm ± 0.00 (p

DOI

10.21608/ejchem.2022.104463.4825

Keywords

Alopecia, Infrared spectroscopy, Sansevieria trifasciata, Anagen, Telogen

Authors

First Name

Henny

Last Name

Kasmawati

MiddleName

-

Affiliation

Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran; Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Halu Oleo

Email

hennykasmawati@uho.ac.id

City

Kendari

Orcid

0000-0002-4355-5933

First Name

Resmi

Last Name

Mustarichie

MiddleName

-

Affiliation

Department of Analytical Pharmacy and Medicinal Chemistry, Faculty of Pharmacy, Universitas Padjadjaran

Email

resmi.mustarichie@unpad.ac.id

City

Bandung

Orcid

0000-0001-6453-0236

First Name

Eli

Last Name

Halimah

MiddleName

-

Affiliation

Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran

Email

eli.halimah@unpad.ac.id

City

Bandung

Orcid

-

First Name

Ruslin

Last Name

Ruslin

MiddleName

-

Affiliation

Department of Analytical Pharmacy and Medicinal Chemistry, Faculty of Pharmacy, Universitas Halu Oleo

Email

mahaleo241@yahoo.co.id

City

Kendari

Orcid

-

First Name

Nurramadhani

Last Name

A Sida

MiddleName

-

Affiliation

Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Halu Oleo

Email

apt.nurramadhani08@gmail.com

City

Kendari

Orcid

-

Volume

65

Article Issue

13

Related Issue

37459

Issue Date

2022-12-01

Receive Date

2021-11-05

Publish Date

2022-12-01

Print ISSN

0449-2285

Online ISSN

2357-0245

Link

https://ejchem.journals.ekb.eg/article_232098.html

Detail API

https://ejchem.journals.ekb.eg/service?article_code=232098

Order

232,098

Type

Original Article

Type Code

297

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry

Publication Link

https://ejchem.journals.ekb.eg/

MainTitle

Antialopecia Activity and IR-Spectrometry Characterization of Bioactive Compounds From Sansevieria trifasciata P.

Details

Type

Article

Created At

22 Jan 2023