This research was run out during 2019 and 2020 seasons, and included two experiments, to study the effect of potassium (K) and calcium (Ca) as a foliar spray on yield and fruit quality of Medjool date palms. Inflorescences of Medjool date palms were sprayed three times (after fruit set then at the beginning of Kimri stage and the third at Khelal stages) in the first experiment with potassium citrate (KC) or potassium nitrate (KN) at 1, 2 and 3%, while in the second experiment, the inflorescences were sprayed with calcium nitrate (CaN) or calcium chloride (CaC) at 0.5, 1 and 1.5%. From the first study results, foliar spray with KN at 3% could be used to improve fruit yield and quality of Medjool dates. In the second study, it could be recommend tospray date palms with CaN at 1% or spraying CaC with 0.5% to obtain a high yield with good fruits properties.