Clothing comfort is essential for any wearer. It is desirable for all apparel products. Tactile and thermal factors are related to human comfort. The aim of this study is to study the effect of new dye based on (Pyrido Pyrimidine Heptadinone Derivative) as new colour dye on some comfort attributes of KES mechanical properties and thermal properties of wool fabric as well as tensile, bending and shear properties. It was found that dyeing process affect tensile energy and tensile extensibility in warp direction, shear rigidity and shear hysteresis in warp directions, bending rigidity in weft direction, and bending hysteresis in both directions. A significant difference was found for compressional properties LC, WC, and RC before and after dyeing. A significant decrease in MIU coefficient of surface friction was found after dyeing wool fabrics in weft direction. Also a significant decrease in thermal conductivity and q max was found after dyeing. The wool fabric under study was found to be used in men's and women's winter suits with total hand values (THV) 4.96 and 4.28 respectively.