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224795

Nano micelle: Novel Approach for Targeted Ocular Drug Delivery System

Article

Last updated: 22 Jan 2023

Subjects

-

Tags

Nano chemistry

Abstract

Ocular delivery like all other systems is challenging for the researchers as one can instill drug into the eye but can never ensure the correct amount reaches the eye. Ophthalmology for all these reasons has commenced its dependence on novel techniques. Ocular through novel becomes a boon as you can deliver huge amounts or you can deliver as per the need but it's always a tricky one as you need more residence of the drug in the eye for better action, but the lacrimal drainage and rejuvenation spoils all novel thoughts and leads the novel with surface modification. The surface of the particles needs to be adhering to the surface of the eye or in the cul de sac as with more drug amount we need more residence for action.
This research work provides a better way for ocular drug delivery to the eye through a novel system, i.e., Nano micelle which consists of tri-block copolymerization with fluoroquinolones for treating gall bacterial infections of the eye. The work is based on how we have employed the nano micelle of a fluoroquinolone for ocular delivery that adheres in the eye and delivers the drug for a period more which cannot be expected through the conventional system.

DOI

10.21608/ejchem.2022.119133.5359

Keywords

Ocular Drug Delivery, Nano micelle, polymers

Authors

First Name

Md Semimul

Last Name

Akhtar

MiddleName

-

Affiliation

Shri Ram Murti Smarak College of Engineering and Technology (Pharmacy), Bareilly-243202, (U.P.), India.

Email

akhtar.mpharm@gmail.com

City

-

Orcid

-

First Name

Sudip Kumar

Last Name

Mandal

MiddleName

-

Affiliation

Dr. B C Roy College of Pharmacy & AHS, Dr. Meghnad Saha Sarani, Bidhannagar, Durgapur, West Bengal- 713206, India.

Email

gotosudip79@gmail.com

City

Durgapur

Orcid

orcid.org/0000-0003-

First Name

Akash

Last Name

Malik

MiddleName

-

Affiliation

Shri Ram Murti Smarak College of Engineering and Technology (Pharmacy), Bareilly-243202, (U.P.), India.

Email

abcd@gmail.com

City

-

Orcid

-

First Name

Anshika

Last Name

Choudhary

MiddleName

-

Affiliation

Shri Ram Murti Smarak College of Engineering and Technology (Pharmacy), Bareilly-243202, (U.P.), India.

Email

abcde@gmail.com

City

-

Orcid

-

First Name

Saiyam

Last Name

Agarwal

MiddleName

-

Affiliation

Shri Ram Murti Smarak College of Engineering and Technology (Pharmacy), Bareilly-243202, (U.P.), India.

Email

abcdef@gmail.com

City

-

Orcid

-

First Name

Sipra

Last Name

Sarkar

MiddleName

-

Affiliation

Department of Pharmaceutical Technology, Brainware University, 398-Ramkrishnapur Road, Barasat, Kolkata-700125, West Bengal, India

Email

abcd1@gmail.com

City

-

Orcid

-

First Name

Suddhasattya

Last Name

Dey

MiddleName

-

Affiliation

Department of Pharmacy, Sanaka Educational Trust`s Group of Institutions, West Bengal713212, India

Email

kuntal.kuni@gmail.com

City

-

Orcid

0000-0002-9209-4133

Volume

65

Article Issue

12

Related Issue

35799

Issue Date

2022-12-01

Receive Date

2022-01-30

Publish Date

2022-12-01

Page Start

337

Page End

355

Print ISSN

0449-2285

Online ISSN

2357-0245

Link

https://ejchem.journals.ekb.eg/article_224795.html

Detail API

https://ejchem.journals.ekb.eg/service?article_code=224795

Order

33

Type

Original Article

Type Code

297

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry

Publication Link

https://ejchem.journals.ekb.eg/

MainTitle

-

Details

Type

Article

Created At

22 Jan 2023