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234756

Synthesis, Characterization, and biological activity of some Heterocyclic compounds that derived from Ibuprofen

Article

Last updated: 01 Jan 2025

Subjects

-

Tags

Organic chemistry

Abstract

A simple, easy method for preparation of new thiazoldine derivatives was done and new compound were elucidated on bases of spectroscopic analyses. Ibuprofen reacted with hydrazine hydrate to afford hydrazide derivative which reacted with aldehydes to afford Schiff bases that cyclized with Thioglycolic acid to afford thiazolidine derivatives. Antimicrobial activity of new compounds was carried out using diffusion plate method.

DOI

10.21608/ejchem.2022.135334.5950

Keywords

Thizaolidine derivatives, antimicrobial activity, spectroscopic analyses

Authors

First Name

Hamid Mohammed Saleh

Last Name

Al-Jubori

MiddleName

-

Affiliation

Department of Science, College of Basic Education/Shirqat, Tikrit University, Tikrit, Iraq

Email

dr.hsaleh@tu.edu.iq

City

-

Orcid

-

First Name

Tahseen Saddam

Last Name

Fandi Al-Mathkuri

MiddleName

-

Affiliation

Department of Chemistry, College of Science, University of Misan, Maysan, Iraq

Email

tahseensaddam@uomisan.edu.iq

City

-

Orcid

0000-0002-6234-0137

Volume

65

Article Issue

11

Related Issue

35761

Issue Date

2022-11-01

Receive Date

2022-04-22

Publish Date

2022-11-01

Page Start

795

Page End

802

Print ISSN

0449-2285

Online ISSN

2357-0245

Link

https://ejchem.journals.ekb.eg/article_234756.html

Detail API

https://ejchem.journals.ekb.eg/service?article_code=234756

Order

234,756

Type

Original Article

Type Code

297

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry

Publication Link

https://ejchem.journals.ekb.eg/

MainTitle

Synthesis, Characterization, and biological activity of some Heterocyclic compounds that derived from Ibuprofen

Details

Type

Article

Created At

22 Jan 2023