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241731

Synthesis, Reactions, and Antimicrobial Evaluation of 2-(1,3-dioxoisoindolin-2-yl)acetohydrazide derivatives

Article

Last updated: 01 Jan 2025

OverviewSimilar Items

Subjects

-

Tags

Organic chemistry

Abstract

New 2-(1,3-dioxoisoindolin-2-yl)acetohydrazide derivatives were synthesized, characterized and evaluated as antimicrobial agents. Phathalic anhydride was reacted with aminoacetoactate to afford phthalimide derivative which reacted with hydrazine hydrate to give new indolinylacetohydrazide derivative 1. Compound 1 is used as precursor to synthesize various derivatives depending on types of reactants. Spectroscopic and analytical measurements are used to confirm structures of new products. Antimicrobial evaluation of new derivatives was done

DOI

10.21608/ejchem.2022.136934.6037

Keywords

acetohydrazide, triazole, thiazolidinone, benzo[e][1, 3]thiazine, antimicrobial evaluation

Authors

First Name

Ban Hasan

Last Name

Taresh

MiddleName

-

Affiliation

Department of Clinical Laboratories, College of Applied Medical Sciences, University of  Kerbala, Kerbala, Iraq

Email

ban.tarsh@uokerbala.edu.iq

City

-

Orcid

-

First Name

Aseel Q

Last Name

Al-saffar

MiddleName

-

Affiliation

College of Pharmacy, Al-Mustansiriyah University, Baghdad, Iraq

Email

lisa1975@uomustansiriyah.edu.iq

City

-

Orcid

-

First Name

Ewies

Last Name

Fawzy

MiddleName

-

Affiliation

Organometallic and Organometalloid Chemistry, Chemical Industries Research Institute, National Research Centre

Email

ewiesfawzy@yahoo.com

City

Giza

Orcid

0000-0002-4832-5766

Volume

65

Article Issue

11

Related Issue

35761

Issue Date

2022-11-01

Receive Date

2022-05-05

Publish Date

2022-11-01

Page Start

541

Page End

548

Print ISSN

0449-2285

Online ISSN

2357-0245

Article File

EJCHEM_Volume 65_Issue 11_Pages 541-548.pdf

PDF . 477.2kB

Link

https://ejchem.journals.ekb.eg/article_241731.html

Detail API

https://ejchem.journals.ekb.eg/service?article_code=241731

Order

50

Type

Original Article

Type Code

297

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry

Publication Link

https://ejchem.journals.ekb.eg/

MainTitle

Synthesis, Reactions, and Antimicrobial Evaluation of 2-(1,3-dioxoisoindolin-2-yl)acetohydrazide derivatives

Details

Type

Article

Created At

22 Jan 2023