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223112

Synthesis & Biological Evaluation of Novel Series of Benzo[f]indazole Derivatives

Article

Last updated: 22 Jan 2023

OverviewSimilar Items

Subjects

-

Tags

Organic chemistry

Abstract

A new series of benzo[f]indazole derivatives was synthesized via cyclo-condensation of β-ketoester with arylidenes derivatives in the presence of alcoholic sodium hydroxide to afford octahydronaphthalene-2-carboxylates. 1,3-Dipolar cycloaddition between these carboxylates and hydrazine hydrate to form benzo[f]indazole derivatives. New obtained compounds were characterized upon elemental and spectroscopic analyses. Antibacterial activity of selected derivatives was evaluated.

DOI

10.21608/ejchem.2022.120818.5418

Keywords

Benzo[f]indazole, Biological evaluation, Chalgone, β- keto ester

Authors

First Name

Ahmed

Last Name

Hamdoon

MiddleName

M

Affiliation

University of Mosul, College of Agriculture and Forestry, Branch of Basic Science

Email

ahmedalhyali@uomosul.edu.iq

City

Mosul

Orcid

-

First Name

Mohanad

Last Name

Saleh

MiddleName

Yakdhan

Affiliation

Department of Chemistry, College of Education for pure science, University of Mosul

Email

mohanadalallaf@uomosul.edu.iq

City

Mosul

Orcid

0000-0003-2320-5167

First Name

shakir

Last Name

Saied

MiddleName

M.

Affiliation

Department of Medical Laboratory Techniques, Al-Noor University College, Mosul-Iraq

Email

shakir.mahmood@alnoor.edu.iq

City

Mosul

Orcid

-

Volume

65

Article Issue

11

Related Issue

35761

Issue Date

2022-11-01

Receive Date

2022-02-08

Publish Date

2022-11-01

Page Start

305

Page End

312

Print ISSN

0449-2285

Online ISSN

2357-0245

Article File

EJCHEM_Volume 65_Issue 11_Pages 305-312.pdf

PDF . 565.2kB

Link

https://ejchem.journals.ekb.eg/article_223112.html

Detail API

https://ejchem.journals.ekb.eg/service?article_code=223112

Order

27

Type

Original Article

Type Code

297

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry

Publication Link

https://ejchem.journals.ekb.eg/

MainTitle

-

Details

Type

Article

Created At

22 Jan 2023