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222067

Comparative study of Some biochemical and Immunological parameters of patients with COVID-19 disease and non-infected people

Article

Last updated: 22 Jan 2023

Subjects

-

Tags

Biochemistry

Abstract

Abstract:
The objective of the present study was to evaluate eight biochemical and Immunological parameters and comparison their level in the infected and non-infected people. The methodology include two parts biochemical assays included aspartate transaminase (AST), alanine aminotransferase (ALT), lactate dehydrogenase (LDH), urea breath test (UREA), and creatinine, and Immunological parameters included D-dimer, ferritin, interleukin 6 (IL-6), C-Reactive Protein (CRP). The result detected by Cobas e411, Cobas C111 device. Results obtained showed high levels of all parameters of covid-19 patients in comparing with the control group patients, with significant differences (p < 0.05). Receiver operating characteristic (ROC) curve showed a high area under the curve for all parameters Area under the ROC Curve (AUC) for all parameters were 1.000, except Patent Cooperation Treaty (PCT) was 0.796) and show high sensitivity for all parameters (sensitivity for all parameters were 100%, except PCT was 75%). The present study was observed significant correlations among the studied of the parameters.

DOI

10.21608/ejchem.2022.113854.5172

Keywords

COVID-19, Liver, kidney, patients, D-Dimer, ferritin

Authors

First Name

Hayder

Last Name

Qaddoori

MiddleName

T

Affiliation

Institute technical baquba, Middle technical university, dayala

Email

haydertawfeeq510@gmail.com

City

Iraq Dayala

Orcid

-

First Name

abdullah

Last Name

hassan

MiddleName

-

Affiliation

chemistry department, college science, diyaia university

Email

abdullahhassan@uodiyala.edu.iq

City

-

Orcid

-

First Name

mohammed

Last Name

Al-shoky

MiddleName

sachit

Affiliation

Al-kut university college, medical laboratory techniques

Email

mohammedsachit@alkutcollege.edu.iq

City

-

Orcid

-

First Name

Yaser

Last Name

K. Kalil

MiddleName

-

Affiliation

College Alqalam University, Karkuk, Iraq

Email

yaserkalil@gmail.com

City

-

Orcid

-

First Name

Mustafa

Last Name

Mudhafar

MiddleName

-

Affiliation

Department of Anesthesia and Intensive Care Techniques, Faculty of AL, Tuff Collage, Karbala, 56001, Iraq

Email

mustafa.mu@gmail.com

City

-

Orcid

-

Volume

65

Article Issue

10

Related Issue

34864

Issue Date

2022-10-01

Receive Date

2021-12-30

Publish Date

2022-10-01

Page Start

217

Page End

223

Print ISSN

0449-2285

Online ISSN

2357-0245

Link

https://ejchem.journals.ekb.eg/article_222067.html

Detail API

https://ejchem.journals.ekb.eg/service?article_code=222067

Order

20

Type

Original Article

Type Code

297

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry

Publication Link

https://ejchem.journals.ekb.eg/

MainTitle

-

Details

Type

Article

Created At

22 Jan 2023