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Cobalt (II), Nickel (II) and Copper (II) complexes of Tetradentate Schiff bases ligands derived from 4-Nitro-O-phenylenediamine: Synthesis, Characterization, cyclic voltammetry an

Article

Last updated: 01 Jan 2025

Subjects

-

Tags

Inorganic chemistry

Abstract

Two tetradentate Schiff base ligands, (N,N'-bis((2-hydroxy-1-phenyl)methylidene)- 4-nitrophenyl-1,2-diamine (H2L1) and N,N'-bis((2-hydroxy-1-naphthyl)methylidene)-4-nitrophenyl-1,2-diamine (H2L2)) have been synthesized by the condensation of 4-nitro-orthophenylenediamine with 2-hydroxy-1-naphthaldehyde and salicylaldehyde respectively in absolute ethanol and reacted with Co(II), Ni(II) and Cu(II) salts to form the corresponding complexes. The compounds were characterized by UV-vis., FT-IR, 1H NMR, 13C NMR, ESI-mass spectra, elemental analysis, and molar conductance measurements. The ligands were found to be tetradentate, coordinating to the metal ions through the azomethine nitrogen and oxygen atoms of phenol and naphthol and the sulphur atoms of thiophenol groups. Conductance measurements shows that these compounds are molecular. Cyclic voltammetry studies shows that the Co(III)/Co(II) and Ni(III)/Ni(II) redox systems are quasi-reversible involving a mono electronic transfer while Cu(III)/Cu(II) is irreversible. In vitro antimicrobial screening against five bacterial strains (Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Enterococcus faecalis, Proteus mirabilis and five fungal strains (Candida albicans, Candida glabrata, Candida tropicalis, Candida krusei, Candida parapsilosis), shows that some of the compounds exhibited moderate antibacterial and antifungal activities compared to the reference drugs. Antioxidant studies reveal that the complexes are more potent than the ligands to eliminate free radicals.
Keywords: Tetradentate Schiff base ligands, 4-nitro-orthophenylenediamine, 2-hydroxy-1-naphthaldehyde, metal complexes, cyclic voltammetry, antimicrobial activity.

DOI

10.21608/ejchem.2022.82313.4087

Keywords

Tetradentate Schiff base ligands, 4-nitro-orthophenylenediamine, 2-hydroxy-1-naphthaldehyde, Metal complexes, Cyclic voltammetry, antimicrobial activity

Authors

First Name

Maurice

Last Name

Kuate

MiddleName

-

Affiliation

Department of Inorganic Chemistry, Faculty of Science, University of Yaoundé I, P.O. Box 812 Yaoundé, Cameroon;

Email

maurice.kuate@yahoo.fr

City

-

Orcid

-

First Name

Evans Ngandung

Last Name

Mainsah

MiddleName

-

Affiliation

Department of Chemistry, Faculty of Science, University of Buea, Cameroon;

Email

evans.mainsah@ubuea.cm

City

-

Orcid

-

First Name

Francis A.

Last Name

Ngounoue Kamga

MiddleName

-

Affiliation

Department of Inorganic Chemistry, Faculty of Science, University of Yaoundé I, P.O. Box 812 Yaoundé, Cameroon;

Email

-

City

-

Orcid

-

First Name

Awawou Gbambi

Last Name

Paboudam

MiddleName

-

Affiliation

Department of Inorganic Chemistry, Faculty of Science, University of Yaoundé I, P.O. Box 812 Yaoundé, Cameroon;

Email

unilawa@yahoo.fr

City

-

Orcid

-

First Name

Conde Asseng

Last Name

Mariam

MiddleName

-

Affiliation

Department of Chemistry, Faculty of Science, University of Douala, Cameroon;

Email

conde_mame@yahoo.fr

City

-

Orcid

-

First Name

Chancellin Nkepdep

Last Name

Peucheu

MiddleName

-

Affiliation

Department of Chemistry, Faculty of Science, University of Dschang, Cameroon.

Email

itonle@yahoo.com

City

-

Orcid

-

First Name

Tonle Kenfack

Last Name

Ignas

MiddleName

-

Affiliation

Department of Chemistry, Faculty of Science, University of Dschang, Cameroon.

Email

itonle@yahoo.cm

City

-

Orcid

-

First Name

Peter T.

Last Name

Ndifon

MiddleName

-

Affiliation

Department of Inorganic Chemistry, Faculty of Science, University of Yaoundé I, P.O. Box 812 Yaoundé, Cameroon;

Email

pndifon@facsciences-uy1.cm

City

Yaoundé

Orcid

0000-0001-9331-9034

Volume

65

Article Issue

9

Related Issue

31876

Issue Date

2022-09-01

Receive Date

2021-06-30

Publish Date

2022-09-01

Page Start

477

Page End

495

Print ISSN

0449-2285

Online ISSN

2357-0245

Link

https://ejchem.journals.ekb.eg/article_215931.html

Detail API

https://ejchem.journals.ekb.eg/service?article_code=215931

Order

46

Type

Original Article

Type Code

297

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry

Publication Link

https://ejchem.journals.ekb.eg/

MainTitle

Cobalt (II), Nickel (II) and Copper (II) complexes of Tetradentate Schiff bases ligands derived from 4-Nitro-O-phenylenediamine: Synthesis, Characterization, cyclic voltammetry and biological studies

Details

Type

Article

Created At

22 Jan 2023