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214293

A Review of Chalcones: Synthesis, Reactions, and Biological Importance

Article

Last updated: 01 Jan 2025

Subjects

-

Tags

Organic chemistry

Abstract

Chalcones are considered an important scaffold in organic compounds. Many of their derivatives have a lot of applications. Therefore, this review was covered some synthesis methods of chalcones such as Claisen-Schmidt's condensation, coupling reaction, continuous-flow deuteration reaction, and other reactions. Also, some reactions were discussed such as the synthesis of seven, six, and five-membered ring heterocyclic compounds. Moreover, some of their biological applications were mentioned like antimicrobial, anticancer, anti-inflammatory, antioxidants, and others with some details.

DOI

10.21608/ejchem.2022.112735.5125

Keywords

Chalcones, Synthesis, Reactions, biological applications

Authors

First Name

Shorouk

Last Name

Mukhtar

MiddleName

S.

Affiliation

Organometallic and Organometalloid Chemistry Department, National Research Centre, Cairo, Dokki 12622, Egypt

Email

chemistshorouk1@yahoo.com

City

-

Orcid

0000-0003-3636-1767

First Name

Nesrin

Last Name

Morsy

MiddleName

M.

Affiliation

Organometallic and Organometalloid Chemistry Department,National Research Centre

Email

nesrinmorsy@yahoo.com

City

-

Orcid

0000-0003-3636-1767

First Name

Ashraf

Last Name

Hassan

MiddleName

S.

Affiliation

Organometallic and Organometalloid Chemistry Department, National Research Centre, Dokki 12622, Cairo, Egypt

Email

ashraf_salmoon@yahoo.com

City

-

Orcid

0000-0002-4771-716X

First Name

Taghrid

Last Name

Hafez

MiddleName

S.

Affiliation

Organometallic and Organometalloid Chemistry Department, National Research Centre, Dokki 12622 Cairo, Egypt

Email

taghridshafez@yahoo.com

City

162622, Cairo

Orcid

0000-0002-1958-3520

First Name

Hamdi

Last Name

Hassaneen

MiddleName

M.

Affiliation

Department of Chemistry, Faculty of Science, Cairo University, Giza, Egypt

Email

hamdi_251@yahoo.com

City

-

Orcid

-

First Name

Fatma

Last Name

Saleh

MiddleName

M.

Affiliation

Department of Chemistry, Faculty of Science, Cairo University, Giza, Egypt

Email

fsaleh@sci.cu.edu.eg

City

-

Orcid

-

Volume

65

Article Issue

8

Related Issue

31862

Issue Date

2022-08-01

Receive Date

2021-12-24

Publish Date

2022-08-01

Page Start

379

Page End

395

Print ISSN

0449-2285

Online ISSN

2357-0245

Link

https://ejchem.journals.ekb.eg/article_214293.html

Detail API

https://ejchem.journals.ekb.eg/service?article_code=214293

Order

35

Type

Review Articles

Type Code

444

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry

Publication Link

https://ejchem.journals.ekb.eg/

MainTitle

A Review of Chalcones: Synthesis, Reactions, and Biological Importance

Details

Type

Article

Created At

22 Jan 2023