Filipendula vulgaris Moench is an important source of different secondary metabolites of beneficial activities on human health. Phytochemical studies showed the presence of many bioactive compounds such as rutin, quercetin, kaempferol, apigenin and phenolic acids. The biological studies of the plant showed antimicrobial, antioxidant and anti-inflammatory. Also, the entire plant oreven its parts (aerial parts, flowers, leaves, roots) were used to treat breathlessness, sore throats, congestion, diarrhea, and rheumatism. The present review summarizes information concerning the biological activities of some compounds isolated from F. vulgaris in addition to their chemical structures.