In orthopedics and traumatology surgeries, the repair of bone deformities is a concern. Pure and cobalt (Co) doped calcium phosphate (CaP) cements were successfully prepared in this study. The particles that had been manufactured were characterized utilizing X-ray powder diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), and Scanning electron microscope (SEM) techniques. The lattice properties, degree of crystallinity, and particle size of pure and modified CaP bone cement were reduced dramatically when added cobalt ions. The functional groups of CaP bone cements were detected via the FTIR technique. Antibacterial properties of pure and Co doped CaP bone cement were evaluated qualitatively against Escherichia coli (E. Coli), Methicillin-sensitive Staphylococcus aureus (MSSA). Methicillin-resistant Staphylococcus aureus (MRSA), Methicillin-resistant coagulase-negative staphylococci (MR-CoNS), and Pseudomonas aeruginosa (P. aeruginosa) bacteria for 24 h at 37 ºC. The results showed that the addition of cobalt ions inhibited the growth of E. coli and MSSA bacteria. Antibacterial bone cements are potential material for preventing infection-related bone healing failures.