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208313

Cathodic Stripping Voltammetric Determination of Lisinopril in Dosage Forms and Biological Fluids

Article

Last updated: 01 Jan 2025

Subjects

-

Tags

Electrochemistry

Abstract

Lisinopril (LSP) in pharmaceutical dosage forms and biological fluids was studied using the square wave cathodic stripping voltammetric method (SWCSV) at a carbon paste electrode (CPE). To maximize the method's circumstances, many parameters were defined. The linear concentration range of 3.53 – 44.17 ng/mL was effectively determined at ideal conditions of 0.08 M Britton-Robinson buffers (pH = 9.00) at accumulation times 15, 30 sec., and 2.64 – 44.17 ng/mL at 60 sec. With good results, the standard addition method was employed to determine LSP in pure solutions, tablets, and biological fluids. The proposed method is compared to the previously published standard method.

DOI

10.21608/ejchem.2021.104642.4835

Keywords

Lisinopril, Cathodic Stripping Voltammetric, Dosage Forms, biological fluids

Authors

First Name

Badriah Saad

Last Name

Al–Farhan

MiddleName

-

Affiliation

Chemistry Department, Faculty of Girls for Science, King Khalid University, Abha, Kingdom of Saudi Arabia

Email

bbbsss30@gmail.com

City

-

Orcid

-

First Name

Ahmed A.

Last Name

Gahlan

MiddleName

-

Affiliation

Chemistry Department, Faculty of Science, Al –Azhar University, Assiut Branch, 71524, Assiut, Egypt

Email

ah4424493@gmail.com

City

Assiut

Orcid

0000-0001-8164-1069

First Name

Ahmed M.

Last Name

Haredy

MiddleName

-

Affiliation

Pharmaceutical Analytical Department, Faculty of Pharmacy, Merit University, New Sohag, Egypt

Email

ahm.mogahed@gmail.com

City

Assiut

Orcid

0000-0002-9019-0818

First Name

Othman A.

Last Name

Fraghly

MiddleName

-

Affiliation

Chemistry Department, Faculty of Science, Al –Azhar University, Assiut Branch, 71524, Assiut, Egypt, Chemistry Department, Faculty of Science, Al Baha University, Al Baha, Kingdom of Saudi Arabia

Email

othman@15yahoo.com

City

Assiut

Orcid

-

Volume

65

Article Issue

7

Related Issue

31861

Issue Date

2022-07-01

Receive Date

2021-11-06

Publish Date

2022-07-01

Page Start

421

Page End

428

Print ISSN

0449-2285

Online ISSN

2357-0245

Link

https://ejchem.journals.ekb.eg/article_208313.html

Detail API

https://ejchem.journals.ekb.eg/service?article_code=208313

Order

41

Type

Original Article

Type Code

297

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry

Publication Link

https://ejchem.journals.ekb.eg/

MainTitle

Cathodic Stripping Voltammetric Determination of Lisinopril in Dosage Forms and Biological Fluids

Details

Type

Article

Created At

22 Jan 2023