Beta
195284

Distribution of Iodine125 Labeled Parathion and the Protective Effect of Dried Banana Peel in Experimental Mice

Article

Last updated: 01 Jan 2025

Subjects

-

Tags

Biochemistry

Abstract

Abstract
Parathion (PA) one of the organophosphorus pesticides, is widespread in agriculture crops. Several studies reported the detection of this pesticide residue in food at high concentrations. Accordingly, the purpose of this study was to determine the accumulation of iodine [125I] labeled parathion ([125I] PA) in mice organs and to study the protecting reflex of dried banana peel. In this study, two groups of mice were used. Iodine [125I] labeled parathion (10 mg/kg body weight) was applied only to one group of mice. Meanwhile, [125I] PA (10 mg/kg body weight) and dried banana peel (20% were added to the diet) were applied to the other group of mice. The mice were injected by [125I] PA through the tail vein and were given the dried banana peel through the mouth. The mice were kept under observation for 180 min. for monitoring. The result of the first group of mice, which was injected with [125I] PA, only indicated that [125I] PA was distributed primarily in the kidneys (18.6%), liver (18.9%), and intestine (6.11%), after 180 min. In the second group of mice which received both [125I] PA, and dried banana peels, [125I] PA accumulated at a lower percentage in the kidneys (10.2%), liver (5.2%), and intestine (4.67%) after 180 min. These results indicated the decrease of [125I] PA in the liver and kidneys could be due to the effect of dried banana peels, and draw attention to the use of agricultural waste to remove pesticide residues contaminating food and feed.

DOI

10.21608/ejchem.2021.92646.4387

Keywords

dried banana peels, parathion, [125I] PA, Biodistribution, Organs, Mice

Authors

First Name

Mahmoud

Last Name

Sanad

MiddleName

-

Affiliation

Food Toxicology and Contaminants Department, National Research Centre, Dokki, Cairo, Egypt.

Email

drsanad74@gmail.com

City

-

Orcid

-

First Name

Emam

Last Name

Abdelrahim

MiddleName

-

Affiliation

Biochemistry Department, Faculty of Agriculture, Cairo University, P. Box 12613, Gamma St, Giza, Egypt

Email

dr.emam.abdelrahim@gmail.com

City

-

Orcid

-

First Name

Amal

Last Name

Hathout

MiddleName

shawaky

Affiliation

Food Toxicology & Contaminant Dept. Food Industry & Nutrition Division National Research Centre El-Bohoth St., 12622 Dokki -Cairo - Egypt

Email

amalhathout@gmail.com

City

Egypt

Orcid

0000-0001-5098-355X

First Name

Omaima

Last Name

Hussain

MiddleName

-

Affiliation

Food Toxicology and Contaminants Department, National Research Centre

Email

omemo2007.oh@gmail.com

City

-

Orcid

-

First Name

Magdy

Last Name

Rashed

MiddleName

-

Affiliation

Chemical Biochemistry Department, University of Agriculture, Cairo University, Giza, Egypt.

Email

magdy.rashed@yahoo.com

City

-

Orcid

-

First Name

ِAhmed

Last Name

Fouzy

MiddleName

-

Affiliation

Food Toxicology &Contaminants Dept., Industries foods & Nutrition Division National Research Centre,33, el behos,Dokki, Egypt.

Email

amoursy@hotmail.com

City

Egypt

Orcid

0000-0001-8178-713x

Volume

65

Article Issue

3

Related Issue

29682

Issue Date

2022-03-01

Receive Date

2021-08-25

Publish Date

2022-03-01

Page Start

203

Page End

214

Print ISSN

0449-2285

Online ISSN

2357-0245

Link

https://ejchem.journals.ekb.eg/article_195284.html

Detail API

https://ejchem.journals.ekb.eg/service?article_code=195284

Order

20

Type

Original Article

Type Code

297

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry

Publication Link

https://ejchem.journals.ekb.eg/

MainTitle

Distribution of Iodine125 Labeled Parathion and the Protective Effect of Dried Banana Peel in Experimental Mice

Details

Type

Article

Created At

22 Jan 2023