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181706

Synthesis, Characterization of Some Copper (II) Complexes with Ampicillin Derivatives and Study their Biological Activity

Article

Last updated: 22 Jan 2023

Subjects

-

Tags

Organic chemistry

Abstract

New metal ion complexes of ampicillin were synthesis by two steps, first by N-acylation with benzoyl chloride and sebacoyl chloride, In the second step, the prepared compounds were reacted with cupric ion to form Cu- complexes. FT-IR, 1H NMR, 13C NMR, UV- visible, Elemental analysis, and, a theoretical study was used to distinguish the prepared complexes. The biological efficacy of synthesis compound was found more active against the bacteria.

DOI

10.21608/ejchem.2021.77649.3789

Keywords

Ampicillin, Copper (II) complexes, Antibacterial activity, AM1 semi-empirical

Authors

First Name

Nahed H.

Last Name

Al-Haidery

MiddleName

-

Affiliation

Chemistry, science faculty, university of Basrah, Iraq

Email

nahidhazim@gmail.com

City

Iraq-Basra

Orcid

-

First Name

Naeem

Last Name

Failli

MiddleName

-

Affiliation

Chemistry, Science faculty, university of Basrah, Iraq

Email

abbas201812@yahoo.com

City

Iraq-Basra

Orcid

-

First Name

Hanan

Last Name

Al-Hazam

MiddleName

-

Affiliation

Chemistry, Science faculty, University of Basrah, Iraq

Email

ha1965nan@yahoo.com

City

Iraq-Basra

Orcid

-

Volume

64

Article Issue

12

Related Issue

27765

Issue Date

2021-12-01

Receive Date

2021-05-25

Publish Date

2021-12-01

Page Start

7,235

Page End

7,240

Print ISSN

0449-2285

Online ISSN

2357-0245

Link

https://ejchem.journals.ekb.eg/article_181706.html

Detail API

https://ejchem.journals.ekb.eg/service?article_code=181706

Order

39

Type

Original Article

Type Code

297

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry

Publication Link

https://ejchem.journals.ekb.eg/

MainTitle

-

Details

Type

Article

Created At

22 Jan 2023