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177936

Study of the effect of laurel plant (Laurus Nobilis) on some biochemical markers in diabetic mellitus rats

Article

Last updated: 01 Jan 2025

Subjects

-

Tags

Biochemistry

Abstract

The present study is aimed to introduce the effect of laurus nobilis extracts on blood glucose level, liver function, lipid profile, and body weight in diabetic rats. Three experiment was done for seventy- two albino male rats (150-200) grams were divided into twelve groups, in each study experiment rats were divided to four groups (6 rats for each) , first group treated with distilled water and served as control group, second group served as positive diabetic and treated with 100 mg/kg, BW single dose of alloxan. Third group treated with 250 mg\kg of oil, flavonoids and tannins extracted from Laurus nobilis, while fourth group was served as diabetic and treated with 250 mg\kg b. w of laurus nobilis extract, all groups were treated orally, the following results were evaluated, fasting blood glucose, triglyceride (TG), total cholesterol (TC), high density lipoprotein-cholesterol (HDL-c), low density lipoprotein-cholesterol (LDL-c), very low density lipoprotein-cholesterol (VLDL-c), alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP) and body weight .After 4 weeks of treating by250 mg\kg BW bay leave extracts there was significant decrease in fasting blood glucose , TG, TC, LDL, VLDL, ALT, AST, ALP, and a significant increase in HDL and body weights.

DOI

10.21608/ejchem.2021.79203.3889

Keywords

Laurus nobilis, laurel plant, oils, Flavonoids, tannins

Authors

First Name

Aser Ihsan

Last Name

Abdullah

MiddleName

-

Affiliation

University of Mosul,College of Science, Department of Chemistry, Mosul, Iraq.

Email

aser.scp49@student.uomosul.edu.iq

City

-

Orcid

-

First Name

Saba Zeki M.

Last Name

AL-Abachi

MiddleName

-

Affiliation

University of Mosul,College of Science, Department of Chemistry, Mosul, Iraq.

Email

-

City

-

Orcid

-

Volume

64

Article Issue

11

Related Issue

27064

Issue Date

2021-11-01

Receive Date

2021-06-05

Publish Date

2021-11-01

Page Start

6,529

Page End

6,540

Print ISSN

0449-2285

Online ISSN

2357-0245

Link

https://ejchem.journals.ekb.eg/article_177936.html

Detail API

https://ejchem.journals.ekb.eg/service?article_code=177936

Order

41

Type

Original Article

Type Code

297

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry

Publication Link

https://ejchem.journals.ekb.eg/

MainTitle

Study of the effect of laurel plant (Laurus Nobilis) on some biochemical markers in diabetic mellitus rats

Details

Type

Article

Created At

22 Jan 2023