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166484

Synthesis and Characterization of Chelating Phenolic Polymers Containing Metoclopramide Hydrochloride Drug

Article

Last updated: 01 Jan 2025

Subjects

-

Tags

Organic chemistry

Abstract

This study in volved synthesis of the chelating phenolic polymers functionalized by Mannich base functional groups. The work included two parts ; part one syntheses of Mannich bases monomers formed by the condensation reaction of P-hydroxy benzaldehyde with different secondary amines and Primary amine (Metoclopramide hydrochloride) have been synthesized. Then part two included synthesis of phenolic chelating polymers containing Mannich bases by condensation Mannich bases which prepared in part one with P-hydroxy benzaldehyde and phenol. These chelating polymers were characterized through (FT-IR) and( 1H-NMR) spectroscopy so measured the thermal stability and study the biological activity of some of the synthesized compounds .

DOI

10.21608/ejchem.2021.44696.2908

Keywords

metoclopramide, chelating phenolic polymers, mannich bases

Authors

First Name

Sameaa

Last Name

Khammas

MiddleName

-

Affiliation

Department of Chemistry; College of Science for Women; University of Baghdad; Baghdad-Iraq

Email

sjk_1975@yahoo.com

City

Iraq -Baghdad

Orcid

-

First Name

Selvana

Last Name

Yosef

MiddleName

-

Affiliation

Department of Chemistry; College of Science for Women; University of Baghdad; Baghdad-Iraq

Email

selvana.chem@gmail.com

City

Iraq -Baghdad

Orcid

-

First Name

Tamador

Last Name

Mahmood

MiddleName

-

Affiliation

Department of Chemistry; College of Science for Women; University of Baghdad; Baghdad-Iraq

Email

tamadhor_mahmaud@yahoo.com

City

Baghdad

Orcid

-

First Name

Wasan

Last Name

Mahmood

MiddleName

-

Affiliation

Department of Chemistry; College of Science for Women; University of Baghdad; Baghdad-Iraq

Email

wasanshaheen28@gmail.com

City

Baghdad

Orcid

0000000232566688

First Name

Shahad

Last Name

Taher

MiddleName

-

Affiliation

Department of Chemistry; College of Science for Women; University of Baghdad; Baghdad-Iraq

Email

shahadkhadim199463@gmail.com

City

Baghdad

Orcid

-

First Name

Muna

Last Name

Hadi

MiddleName

-

Affiliation

Department of Chemistry; College of Science for Women; University of Baghdad; Baghdad-Iraq

Email

munabilal714@gmail.com

City

Baghdad

Orcid

-

Volume

64

Article Issue

9

Related Issue

27062

Issue Date

2021-09-01

Receive Date

2020-10-01

Publish Date

2021-09-01

Page Start

4,973

Page End

4,984

Print ISSN

0449-2285

Online ISSN

2357-0245

Link

https://ejchem.journals.ekb.eg/article_166484.html

Detail API

https://ejchem.journals.ekb.eg/service?article_code=166484

Order

27

Type

Original Article

Type Code

297

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry

Publication Link

https://ejchem.journals.ekb.eg/

MainTitle

Synthesis and Characterization of Chelating Phenolic Polymers Containing Metoclopramide Hydrochloride Drug

Details

Type

Article

Created At

22 Jan 2023