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165437

Chemical constituents from Sarcostemma acidum (Roxb.) Voigt

Article

Last updated: 01 Jan 2025

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Subjects

-

Tags

Organic chemistry

Abstract

Sarcostemma acidum (Roxb.) Voigt is a valuable medicinal plant to treat a number of diseases in India. Four compounds were isolated from the whole plant of S. acidum. The structures were characterized as Friedelin (1), β-amyrin (2), β-sitosterol (3) and 4α-Carboxy-4β-methyl-5α-cholesta-8,24-dien-3β-ol (4) by extensive spectroscopic (NMR, FT-IR and mass) analysis and compared their spectral data with literature. The in vitro anti-inflammatory activity of isolated compounds (1-4) and extract of S. acidum was carried out against the denaturation of protein using egg albumin method compared with standard dichlofenac sodium. The compounds showed the inhibition of protein denaturation in a concentration dependent manner.

DOI

10.21608/ejchem.2021.62105.3336

Keywords

S. acidum, triterpenoid, isolation, Anti-inflammatory

Authors

First Name

Deepjyoti

Last Name

Dutta

MiddleName

-

Affiliation

Chemical Science and Technology Division, CSIR-North East Institute of Science & Technology, Jorhat 785006, Assam, India, Department of Chemistry, Sikkim Manipal University (Sikkim Manipal Institute of Technology), Majitar 737136, Sikkim, India

Email

deepjyoti13288@gmail.com

City

Jorhat

Orcid

-

First Name

Manobjyoti

Last Name

Bordoloi

MiddleName

-

Affiliation

Chemical Science and Technology Division, CSIR-North East Institute of Science & Technology, Jorhat 785006, Assam, India

Email

mjb_rrlj@yahoo.co.in

City

-

Orcid

-

First Name

Nayan

Last Name

Bhattacharyya

MiddleName

-

Affiliation

Department of Chemistry, Sikkim Manipal University (Sikkim Manipal Institute of Technology), Majitar 737136, Sikkim, India

Email

nkamalbhatt@gmail.com

City

Majitar, Rangpo

Orcid

0000-0002-4590-5298

Volume

64

Article Issue

9

Related Issue

27062

Issue Date

2021-09-01

Receive Date

2021-02-08

Publish Date

2021-09-01

Page Start

4,815

Page End

4,819

Print ISSN

0449-2285

Online ISSN

2357-0245

Article File

EJCHEM_Volume 64_Issue 9_Pages 4815-4819.pdf

PDF . 306.7kB

Link

https://ejchem.journals.ekb.eg/article_165437.html

Detail API

https://ejchem.journals.ekb.eg/service?article_code=165437

Order

11

Type

Original Article

Type Code

297

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry

Publication Link

https://ejchem.journals.ekb.eg/

MainTitle

Chemical constituents from Sarcostemma acidum (Roxb.) Voigt

Details

Type

Article

Created At

22 Jan 2023