Beta
ManageSearchChatDiscover
165436

Antimicrobial Compound Isolated From The Plant Pothos scandens L.

Article

Last updated: 01 Jan 2025

OverviewSimilar Items

Subjects

-

Tags

Organic chemistry

Abstract

Abstract

Pothos scandens L. is a medicinal plant found in North East India with various ethno-medicinal activities. A compound was isolated from the bark of P. scandens and the structure was characterized as Octyl isonicotinate (1) by extensive NMR, FT-IR and mass analysis. Compound 1 exhibited significant antimicrobial activity against Escherichia coli and Candida albicans by Agar well diffusion method with zone of inhibition value of 9.16±0.28 mm and 12.5±0.51 mm, respectively compared with standard Amikacin (19.33±0.57) and Fluconazole (15.9± 0.12). The minimum inhibitory concentration (MIC) values were found 12.30 µg/mL and 6.50 µg/mL respectively as compared to Amikacin (4.37 µg/mL) and Fluconazole (7.5µg/mL).

DOI

10.21608/ejchem.2021.56540.3216

Keywords

Pothos scandens, Octyl isonicotinate, Antimicrobial

Authors

First Name

Deepjyoti

Last Name

Dutta

MiddleName

-

Affiliation

Chemical Science and Technology Division, CSIR-North East Institute of Science & Technology, Jorhat 785006, Assam, India, Department of Chemistry, Sikkim Manipal University (Sikkim Manipal Institute of Technology), Majitar 737136, Sikkim, India

Email

deepjyoti13288@gmail.com

City

Jorhat

Orcid

-

First Name

Manob

Last Name

Bordoloi

MiddleName

-

Affiliation

Chemical Science and Technology Division, CSIR-North East Institute of Science & Technology, Jorhat 785006, Assam, India

Email

mjb_rrlj@yahoo.co.in

City

-

Orcid

-

First Name

Nayan

Last Name

Bhattacharyya

MiddleName

-

Affiliation

Department of Chemistry, Sikkim Manipal University (Sikkim Manipal Institute of Technology), Majitar 737136, Sikkim, India

Email

nkamalbhatt@gmail.com

City

Majitar, Rangpo

Orcid

0000-0002-4590-5298

Volume

64

Article Issue

9

Related Issue

27062

Issue Date

2021-09-01

Receive Date

2021-01-04

Publish Date

2021-09-01

Page Start

4,803

Page End

4,807

Print ISSN

0449-2285

Online ISSN

2357-0245

Article File

EJCHEM_Volume 64_Issue 9_Pages 4803-4807.pdf

PDF . 220.8kB

Link

https://ejchem.journals.ekb.eg/article_165436.html

Detail API

https://ejchem.journals.ekb.eg/service?article_code=165436

Order

9

Type

Original Article

Type Code

297

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry

Publication Link

https://ejchem.journals.ekb.eg/

MainTitle

Antimicrobial Compound Isolated From The Plant Pothos scandens L.

Details

Type

Article

Created At

22 Jan 2023