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148101

Synthesis, Identification and Study of the Anti-microbial Activity of Novel Chalcone and Epoxy Chalcone Compounds

Article

Last updated: 22 Jan 2023

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Tags

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Abstract

Abstract
In this study, new chalcone and epoxy chalcone synthesized by condensation of 4-acetylbiphenyl with the appropriate aldehydes. The epoxy chalcone prepared via the reaction chalcone with alkaline hydrogen peroxide in methanol. We characterized their mass spectra and 1H, 13C-NMR, and 2D-HSQC spectra to confirm their structure and absolute configuration. The target compounds were then screened for their potential antibacterial and antifungal activities. Most of the tested chalcone compounds had better activity against the fungal strains Fusarium and Aspergillus niger.

DOI

10.21608/ejchem.2021.57012.3233

Keywords

Chalcone, Epoxy Chalcone, Green chemistry, Anti-microbial activity

Authors

First Name

Kawkab

Last Name

Ali

MiddleName

-

Affiliation

Department of Chemistry, College of Education for Pure Sciences, University of Basrah , Basrah, Iraq

Email

kawkab.ali@uobasrah.edu.iq

City

Basrah

Orcid

0000-0001-9796-0929

First Name

Nezar

Last Name

Shihab

MiddleName

latif

Affiliation

Department of Chemistry, College of Education for Pure Sciences, University of Basrah, Basrah, Iraq.

Email

nezar.latif@uobasrah.edu.iq

City

Basrah

Orcid

-

First Name

Bahjat

Last Name

saeed

MiddleName

ali

Affiliation

Department of Chemistry, College of Education for Pure Sciences, University of Basrah, Basrah, Iraq.

Email

bahjat.saeed@uobasrah.edu.iq

City

Basrah

Orcid

-

Volume

64

Article Issue

5

Related Issue

23661

Issue Date

2021-05-01

Receive Date

2021-01-14

Publish Date

2021-05-01

Page Start

2,297

Page End

2,304

Print ISSN

0449-2285

Online ISSN

2357-0245

Article File

EJCHEM_Volume 64_Issue 5_Pages 2297-2304.pdf

PDF . 564.0kB

Link

https://ejchem.journals.ekb.eg/article_148101.html

Detail API

https://ejchem.journals.ekb.eg/service?article_code=148101

Order

6

Type

Original Article

Type Code

297

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry

Publication Link

https://ejchem.journals.ekb.eg/

MainTitle

-

Details

Type

Article

Created At

22 Jan 2023