Zinc oxide nano-rod thin films (ZNR) will be deposited on silicon substrate (ZNRS) and borosilicate glass capillary tube tip (0.5 and 0.7 µm as inner and outer diameters, respectively) (ZNRT) using both Sol-Gel (SG) and aqueous chemical growth (ACG) techniques for glucose biosensor fabrication. It will be functionalized with membranes or enzymes to produce selective glucose biosensor for glucose concentration measurements in extracellular solutions. The prepared thin film samples provided a favourable environment for the glucose oxidase (GOD) immobilization and introduced a shuttling way for electronic communication between electrodes and GOD. The prepared ZNRS and ZNRT structures and morphologies will be characterized by X-ray diffraction (XRD) and Field emission high resolution scanning electron microscopy (FESEM).