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117237

pH Assists For Selective Determination Of Acyclovir By The Emission Enhancement Of Tb3+Chemosensor In Tablet And Serum Samples

Article

Last updated: 22 Jan 2023

OverviewSimilar Items

Subjects

-

Tags

Analytical chemistry

Abstract

A new selective method for the determination of acyclovir in tablets and serum samples was developed. The method depends on the luminescence enhancement of Tb3+ chemo sensor with different concentrations of acyclovir at pH 10. Acyclovir can form a complex with Tb3+ ion of 1:3 molar ratio in DMSO. The luminescence intensity of Tb3+-acyclovir complex increases as the concentration of the drug increases at λex=320 nm, pH 10 in DMSO. The linear range for determination of the selected drug in DMSO 1.0 x 10-9 –1 x 10-5 mol L-1 the detection limits were 0.24 x 10-9 mol L-1.

DOI

10.21608/ejchem.2020.40799.2826

Keywords

Acyclovir, Tb- Acyclovir complex, Luminescence Intensity, Enhancement

Authors

First Name

tarek

Last Name

amin

MiddleName

ahmed

Affiliation

Chem. Dep., Fac. of Sci., Ain Shams Uni.

Email

besteye555@hotmail.com

City

Abbassia

Orcid

-

First Name

mohamed

Last Name

azeb

MiddleName

emad

Affiliation

Chem. Dep., Fac. of Sci., Ain Shams Uni.

Email

saidattiasam78@gmail.com

City

Abbassia

Orcid

-

First Name

Mohamed Sabry

Last Name

Abdel-Mottaleb

MiddleName

Ahmed

Affiliation

Department of Chemistry, Faculty of Science, Ain Shams University

Email

m.s.abdelmottaleb@sci.asu.edu.eg

City

Cairo

Orcid

0000-0002-4437-7040

First Name

Mohamed

Last Name

Attia

MiddleName

Said

Affiliation

Chemistry Department, Faculty of Science, Ain Shams University, Abbassia, Cairo, Egypt

Email

mohamed_sam@yahoo.com

City

-

Orcid

-

Volume

64

Article Issue

2

Related Issue

21013

Issue Date

2021-02-01

Receive Date

2020-08-27

Publish Date

2021-02-01

Page Start

713

Page End

720

Print ISSN

0449-2285

Online ISSN

2357-0245

Article File

EJCHEM_Volume 64_Issue 2_Pages 713-720.pdf

PDF . 617.1kB

Link

https://ejchem.journals.ekb.eg/article_117237.html

Detail API

https://ejchem.journals.ekb.eg/service?article_code=117237

Order

14

Type

Original Article

Type Code

297

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry

Publication Link

https://ejchem.journals.ekb.eg/

MainTitle

-

Details

Type

Article

Created At

22 Jan 2023