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104319

Heterogeneous Acid Catalyzed Synthesis and Spectroscopic Characterization of Schiff Bases Derived from Chalcone Derivatives

Article

Last updated: 01 Jan 2025

OverviewSimilar Items

Subjects

-

Tags

Organic chemistry

Abstract

Schiff bases have continued to gain attention as essential building blocks and versatile pharmacophores in drug development and drug-like molecular entities. Thus, the synthesis of Schiff bases was achieved herein via facile acetic acid catalyzed synthetic transformation of chalcones. The targeted Schiff bases and related compounds 2a-m were accessed by the treatment of amines with chalcone 1 which was previously derived through Claisen-Schmidt reaction between benzaldehyde and acetone, at ambient temperature. Structural characterization was achieved via physicochemical properties and the use of IR, UV, 1H and 13C NMR which were spectroscopic techniques. The compounds have essential candidature for further study, in biological activity so as to unleash their medicinal potential.

DOI

10.21608/ejchem.2020.20610.2233

Keywords

Chalcone, azomethine, substituted benzaldehyde, heterogenous catalyst

Authors

First Name

Olayinka

Last Name

Ajani

MiddleName

Oyewale

Affiliation

Department of Chemistry, College of Science and Technology. Covenant University. Km 10, Idiroko Road, PMB 1023, Ota. Ogun State, Nigeria

Email

ola.ajani@covenantuniversity.edu.ng

City

Ota

Orcid

0000-0002-3422-3478

First Name

Emmanuel

Last Name

Jolayemi

MiddleName

G.

Affiliation

Department of Chemistry, CST, Covenant University, Km 10, Idiroko Road, Ota, Ogun State, Nigeria

Email

emmanuel.jolayemi@covenantuniversity.edu.ng

City

Ota

Orcid

-

First Name

Fisayo

Last Name

Owolabi

MiddleName

Elizabeth

Affiliation

Department of Chemistry, CST, Covenant University. Km 10, Idiroko Road, Ota, Ogun State, Nigeria

Email

fisayo.owolabi@covenantuniversity.edu.ng

City

Ota

Orcid

-

First Name

Olayinka

Last Name

Tolubolaji

MiddleName

O.

Affiliation

Department of Chemistry, CST, Covenant University. Km 10, Idiroko Road, Ota, Ogun State, Nigeria

Email

olayinkatolubolaji@gmail.com

City

Ota

Orcid

-

First Name

Oluwatosin

Last Name

Audu

MiddleName

Yemisi

Affiliation

Department of Chemistry, University of Pretoria, South Africa

Email

kemitosin2@gmail.com

City

Ota

Orcid

0000-0002-7174-4432

Volume

64

Article Issue

1

Related Issue

19680

Issue Date

2021-01-01

Receive Date

2019-12-06

Publish Date

2021-01-01

Page Start

193

Page End

200

Print ISSN

0449-2285

Online ISSN

2357-0245

Article File

EJCHEM_Volume 64_Issue 1_Pages 193-200.pdf

PDF . 800.2kB

Link

https://ejchem.journals.ekb.eg/article_104319.html

Detail API

https://ejchem.journals.ekb.eg/service?article_code=104319

Order

20

Type

Original Article

Type Code

297

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry

Publication Link

https://ejchem.journals.ekb.eg/

MainTitle

Heterogeneous Acid Catalyzed Synthesis and Spectroscopic Characterization of Schiff Bases Derived from Chalcone Derivatives

Details

Type

Article

Created At

22 Jan 2023