Bleached cotton fabrics were pre-treated with moringa leaf extract as natural bioactive materials to impart the fabric dual antimicrobial and sun protective properties. The fabrics were the treated with TiO2NP and ZnONP separately with concentration 2%&1% respectivelyin presence of butane tetracarboxlyic acid as non-formaldehyde crosslinking agent by pad dry cure technique. The treated fabrics were evaluated via monitoring morphological changes of the fibers using scanning electron microscopy and electron diffraction X-ray (SEM&EDX), tensile strength, roughness, ultra violet factor (UPF) in addition to bioas-say of antimicrobial activity of the treated fabrics. Research output disclosed that the fabrics treated with moringa extract and then with titanium dioxide nanometal oxide powder show the best results.