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68319

Synthesis of Novel N- and C-acyclic Nucleosides Derived from 2-hydrazino-6-methyluracil

Article

Last updated: 01 Jan 2025

Subjects

-

Tags

Organic chemistry

Abstract

The reaction of 2-hydrazino-6-methyl uracil with different aldo- sugars yields the corresponding N-acyclic glycosides. However, some of them have cyclized successfully to form a new fused triazole ring. Apparently, such cyclization depends upon the Stereochemistry of the N-glycoside intermediates that produce the C-glycosides."

DOI

10.21608/ejchem.2020.21459.2279

Keywords

Uracil, N-glycoside, C-glycoside, acyclic nucleoside

Authors

First Name

Hayam A.

Last Name

Abd El Salam

MiddleName

-

Affiliation

Green Chemistry Department, National Research Centre, 33 EL Bohouthst. (former EL Tahrirst.) – Dokki – Giza – Egypt - P.O.12622.

Email

hayam_nrc@yahoo.com

City

cairo

Orcid

0000-0003-3848-3450

First Name

A.M.

Last Name

Gaafar

MiddleName

-

Affiliation

Department of Photochemistry,National Research Centre, 33 EL Bohouthst. (former EL Tahrirst.) – Dokki – Giza – Egypt - P.O.12622

Email

alaa09@gmail.com

City

Cairo

Orcid

-

Volume

63

Article Issue

7

Related Issue

10593

Issue Date

2020-07-01

Receive Date

2019-12-25

Publish Date

2020-07-01

Page Start

2,775

Page End

2,781

Print ISSN

0449-2285

Online ISSN

2357-0245

Link

https://ejchem.journals.ekb.eg/article_68319.html

Detail API

https://ejchem.journals.ekb.eg/service?article_code=68319

Order

29

Type

Original Article

Type Code

297

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry

Publication Link

https://ejchem.journals.ekb.eg/

MainTitle

Synthesis of Novel N- and C-acyclic Nucleosides Derived from 2-hydrazino-6-methyluracil

Details

Type

Article

Created At

22 Jan 2023