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66033

Synthesis,Spectroscopic Investigation, Anti-Bacterial and Antioxidant Activites of Some New Azo-Benzofuran Derivatives

Article

Last updated: 01 Jan 2025

OverviewSimilar Items

Subjects

-

Tags

Organic chemistry

Abstract

This Article deals with the stepwise synthesis and spectroscopic characterization of some new azo benzofuran derivatives, started from the diazotization of substituted aniline coupled with 2-hydroxy benzaldehyde. On reacting of the azo of 2-hydroxy benzaldehyde with p-bromo phenacyl bromide, the benzofuran (3a-g) are obtained. The structure of the new benzofuran derivatives have been characterized by using FT-IR, 1H-NMR,13C-NMR and DEPT-135 NMR. The biological activity of some new synthesized compound was obtained by vitro anti oxidant and anti microbial activity with both Staphylococcus aureus and Escherichia coli .The results showed that the new benzofurans have mild anti oxidant activity compared to the standard ascorbic acid.

DOI

10.21608/ejchem.2019.14844.1899

Keywords

Synthesis, Diazotization, benzofurans, antimicrobial activity, Antioxidant activity

Authors

First Name

Mzgin

Last Name

Ayoob

MiddleName

M.

Affiliation

Department of Chemistry, college of education, Salahaddin University-Erbil

Email

mzgin.ayoob@su.edu.krd

City

-

Orcid

0000-0001-9828-7828

First Name

farouq

Last Name

Hawaiz

MiddleName

E

Affiliation

Department of Chemistry, College of Education, Salahaddin University – Hawler, Erbil-Kurdistan, Iraq

Email

farouq.hawaiz@su.edu.krd

City

-

Orcid

-

First Name

Awaz

Last Name

hussein

MiddleName

-

Affiliation

Department of Chemistry, College of Education, Salahaddin University – Hawler, Erbil-Kurdistan, Iraq

Email

awaz.hussein@su.edu.krd

City

-

Orcid

-

First Name

mohammed

Last Name

Samad

MiddleName

K.

Affiliation

Department of Chemistry, College of Education, Salahaddin University – Erbil Erbil-Kurdistan, Iraq

Email

mohammed.samad@su.edu.krd

City

-

Orcid

0000-0003-0725-4014

First Name

Faiq

Last Name

Hussain

MiddleName

-

Affiliation

TIU, Research Center, Tishk International University, Erbil, Iraq

Email

faiq.hussain@su.edu.krd

City

-

Orcid

-

First Name

Shaaban

Last Name

Mohamed

MiddleName

K

Affiliation

Division of Chemistry and Environmental Science, Manchester Metropolitan University, Manchester,, United Kingdom

Email

shaabankamel@yahoo.com

City

-

Orcid

-

Volume

63

Article Issue

7

Related Issue

10593

Issue Date

2020-07-01

Receive Date

2019-07-15

Publish Date

2020-07-01

Page Start

2,617

Page End

2,629

Print ISSN

0449-2285

Online ISSN

2357-0245

Article File

EJCHEM_Volume 63_Issue 7_Pages 2617-2629.pdf

PDF . 1.9MB

Link

https://ejchem.journals.ekb.eg/article_66033.html

Detail API

https://ejchem.journals.ekb.eg/service?article_code=66033

Order

17

Type

Original Article

Type Code

297

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry

Publication Link

https://ejchem.journals.ekb.eg/

MainTitle

Synthesis,Spectroscopic Investigation, Anti-Bacterial and Antioxidant Activites of Some New Azo-Benzofuran Derivatives

Details

Type

Article

Created At

22 Jan 2023