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68320

Synthesis, Molecular Modeling and Biological Evaluation of Indeno[1,2-b]quinoxaline Derivatives as Antifungal and Antibacterial Agents

Article

Last updated: 22 Jan 2023

OverviewSimilar Items

Subjects

-

Tags

Organic chemistry

Abstract

The (11H-indeno[1,2-b]quinoxalin-11-ylidene)thiocarbohydrazonewere synthesized and consequently some new novel structures were obtained in a good yields. Their chemical structures were assigned by means of spectral analysis. Molecular modeling at B3LYP/6-31 g (d, p) is utilized to calculate both the optimized structure and vibrational spectra of some studied structures. A promising antimicrobial result was obtained from the new synthesized compounds.

DOI

10.21608/ejchem.2020.21366.2275

Keywords

11Н-Indeno [1, 2-b]quinoxalin-2-one, Thiocarbohydrazides, 2- Chloroacetamide derivatives, Molecular modeling, antimicrobial activity

Authors

First Name

Hayam A.

Last Name

Abd El salam

MiddleName

-

Affiliation

Green Chemistry Department, Chemical Industrial Research Division, National Research Centre.

Email

hayam_nrc@yahoo.com

City

cairo

Orcid

0000-0003-3848-3450

First Name

Magda A.

Last Name

El-Bendary

MiddleName

-

Affiliation

Microbial Chemistry Department, Genetic Engineering and Biotechnology Division, National Research Centre.

Email

-

City

-

Orcid

-

First Name

Medhat

Last Name

Ibrahim

MiddleName

-

Affiliation

Spectroscopy Department, National Research Centre, 33 El-Bohouth St, Dokki, Giza, Egypt, P.O.12622.

Email

medhat.ibrahim@gmail.com

City

-

Orcid

-

First Name

Fatma A.

Last Name

El-Samahy

MiddleName

-

Affiliation

Green Chemistry Department, Chemical Industrial Research Division, National Research Centre.

Email

samahyf@hotmail.com

City

-

Orcid

-

Volume

63

Article Issue

7

Related Issue

10593

Issue Date

2020-07-01

Receive Date

2019-12-24

Publish Date

2020-07-01

Page Start

2,577

Page End

2,590

Print ISSN

0449-2285

Online ISSN

2357-0245

Article File

EJCHEM_Volume 63_Issue 7_Pages 2577-2590.pdf

PDF . 1.8MB

Link

https://ejchem.journals.ekb.eg/article_68320.html

Detail API

https://ejchem.journals.ekb.eg/service?article_code=68320

Order

14

Type

Original Article

Type Code

297

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry

Publication Link

https://ejchem.journals.ekb.eg/

MainTitle

-

Details

Type

Article

Created At

22 Jan 2023