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69321

Synthesis of Some New Aryl-azo Derivatives Clubbed with Pyridone and Evaluating their Biological Broadcast

Article

Last updated: 01 Jan 2025

OverviewSimilar Items

Subjects

-

Tags

Organic chemistry

Abstract

SYNTHESIS of some new Aryl-azopyridone analogues was synthesized through coupling of diverse Diazonium salts with 1-ethyl-4-methyl-2,6-dioxopiperidine-3-carbonitrile. The proper structures for all incorporated derivatives were demonstrated to be confirmed via various physical and spectral analyses performed. The synthesized analogues were probed as cytotoxic agents toward four dissimilar cell lines, in which the results displayed persuasive activities relative to the results of antibiotic standards. In addition, the antioxidant activity of the synthesized analogues was evaluated using ABTS•+ method.

DOI

10.21608/ejchem.2020.22449.2335

Keywords

Anticancer activities, antioxidant, Cytotoxicity, Diazonium salts, Pyridones

Authors

First Name

Hatem

Last Name

Gaffer

MiddleName

-

Affiliation

Dyeing, Printing and Auxiliaries Department, Textile Industries Research Division, National Research Centre, 33 El-Buhouth Street, Dokki, Cairo 12622, Egypt.

Email

hatem197@yahoo.com

City

Cairo

Orcid

-

First Name

Morsy

Last Name

Elapasery

MiddleName

-

Affiliation

Dyeing, Printing and Auxiliaries Department, Textile Research Division, National Research Centre, Cairo 12622, Egypt

Email

elapaserym@yahoo.com

City

Cairo

Orcid

0000-0002-4686-2007

First Name

Dina

Last Name

Abbas

MiddleName

-

Affiliation

Dyeing, Printing and Auxiliaries Department, Textile Industries Research Division, National Research Centre, 33 El-Buhouth Street, Dokki, Cairo 12622, Egypt.

Email

eng_buny2009@yahoo.com

City

Cairo

Orcid

-

First Name

Emad

Last Name

Allam

MiddleName

-

Affiliation

Textile Printing, Dyeing and Finishing Department, Faculty of Applied Arts Helwan University, Cairo 12622, Egypt.

Email

allam2019@yahoo.com

City

Cairo

Orcid

-

Volume

63

Article Issue

3

Related Issue

10589

Issue Date

2020-03-01

Receive Date

2020-01-14

Publish Date

2020-03-01

Page Start

1,087

Page End

1,099

Print ISSN

0449-2285

Online ISSN

2357-0245

Article File

EJCHEM_Volume 63_Issue 3_Pages 1087-1099.pdf

PDF . 1.2MB

Link

https://ejchem.journals.ekb.eg/article_69321.html

Detail API

https://ejchem.journals.ekb.eg/service?article_code=69321

Order

276

Type

Original Article

Type Code

297

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry

Publication Link

https://ejchem.journals.ekb.eg/

MainTitle

Synthesis of Some New Aryl-azo Derivatives Clubbed with Pyridone and Evaluating their Biological Broadcast

Details

Type

Article

Created At

22 Jan 2023