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Novel Heterocycles via 2-Cyano-N-arylacetamide Synthesis with Docking Studies of Novel Heterocycles as Antimicrobial Agents Utilizing 2-Cyano-N-arylacetamide

Article

Last updated: 01 Jan 2025

OverviewSimilar Items

Subjects

-

Tags

Organic chemistry

Abstract

2-CYANO-N-arylacetamide reagent is used in a straight forward synthesis of various interesting nitrogenous heterocycles such as iminocoumarine, thiazole, dihydropyridine and imidazole or benzoimidazole. Molecular docking studies are described to show the most active compounds as antimicrobial agents. Also, Biological testing of these compounds for their antimicrobial activities against some strains of Gram bacteria and strains of fungi has been carried out.

DOI

10.21608/ejchem.2020.21812.2294

Keywords

Antimicrobial activities, 2-Cyano-N-arylacetamide, Iminocoumarine, Thiazole and Dihydropyridine

Authors

First Name

Hayam

Last Name

Abdelsalaam

MiddleName

A.

Affiliation

Department of Green Chemistry, National Research Centre (NRC), 33 EL-Bohouth Street (former EL-Tahrir Street), Dokki Giza Egypt

Email

hayam_nrc@yahoo.com

City

cairo

Orcid

0000-0003-3848-3450

First Name

Ewies

Last Name

Ewies

MiddleName

-

Affiliation

Organometallic and Organometalloid Chemistry, Chemical Industries Division, National Research Centre

Email

ewiesfawzy@yahoo.com

City

Giza

Orcid

0000-0002-4832-5766

Volume

63

Article Issue

3

Related Issue

10589

Issue Date

2020-03-01

Receive Date

2020-01-01

Publish Date

2020-03-01

Page Start

1,075

Page End

1,085

Print ISSN

0449-2285

Online ISSN

2357-0245

Article File

EJCHEM_Volume 63_Issue 3_Pages 1075-1085.pdf

PDF . 9.4MB

Link

https://ejchem.journals.ekb.eg/article_69320.html

Detail API

https://ejchem.journals.ekb.eg/service?article_code=69320

Order

275

Type

Original Article

Type Code

297

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry

Publication Link

https://ejchem.journals.ekb.eg/

MainTitle

Novel Heterocycles via 2-Cyano-N-arylacetamide Synthesis with Docking Studies of Novel Heterocycles as Antimicrobial Agents Utilizing 2-Cyano-N-arylacetamide

Details

Type

Article

Created At

22 Jan 2023