In coloration of fabrics, natural dye shows more environmental advantages than synthetic dyes; however, the product has poorer color and fastness properties. The present study showed the suitability of printing most kind of fabrics (natural synthetic and blends) with natural dye using pigment printing technique assist by plasma radiation with high product quality. The effect of different factors was studied as plasma conditions (power & exposure time), binder's concentration, fabric type and structure of natural dye. Various measurements as SEM, AFM, and EDX evaluated the effect of plasma treatment on the fabric surface. The gained results of both color strength (K/S ) and fastness properties showed a great extent in enhancing printability and indicating that plasma treatment of printed fabrics with natural dye has high K/S values and excellent fastness properties comparing with the blank sample.