Some metal salts can react with 3-amino-1,2,4-triazole derivatives as Ni(II) acetate, Co(II) acetate and Cu(II) acetate afforded metallated products Ia-d, IIa-d and IIIa-e in the form of monometal, dimetal, and metal bis products. Elemental analyses, IR, 1H NMR, 13C NMR and mass spectral elucidated the structures of the newly synthesized compounds.
Some of the azo metal compounds were treated with silver nanoparticles. Transmission electron microscopy is used to determine the morphology and particles size via TEM image of nanoparticles and nano form of compounds. The antimicrobial activity of the recently synthesized compounds and its nano form has been measured against gram positive and gram negative bacteria and fungi.