Flexible packaging materials is one of the huge sectors in packaging industries which feed wide range of industries etc. food, medical, beverage and others daily used products. Different structures of flexible packaging materials and its functional properties have been discussed. Ten popular multilayer laminated structures have been evaluated. These laminates are used extensively in the flexible packaging sector to demand various application purposes. The evaluation of these multilayer structures was conducted by assessment of barrier properties, mechanical properties and overall migration rates. The barrier properties were investigated by measurement of water vapor and oxygen permeability. The mechanical properties were studied through measurement the tensile strength and elongation at break %. The overall migration was tested for all samples according to EU Regulation Nr. 10/2011. The different structures showed highly satisfied functional properties that needed for each application.