Beta
ManageSearchChatDiscover
7331

Reno-protective Effect of Methanolic Extract of Stevia Rebaudiana Bertoni and Bioactive Phenolic Compounds In Type-1- Diabetes

Article

Last updated: 22 Jan 2023

OverviewSimilar Items

Subjects

-

Tags

Organic chemistry

Abstract

The aim of this study is to evaluate the reno-protective effect of the defatted methanolic extract of Stevia rebaudiana which showed the highest improvement of renal parameters, as it reduced the protein urea, blood urea nitrogen and blood creatinine and nephroprotective properties with reduced hyperglycemia complications through protection of renal tissues in type-1 diabetes. Also, identification of bioactive phenolic compounds of defatted methanolic extract using HPLC analysis, demonstrate the presence of diterpene glycosides, stevioside, rebaudioside A and chlorogenic acid

DOI

10.21608/ejchem.2018.3550.1297

Keywords

Stevia rebaudiana, diterpene glycosides, chlorogenic acid, Phenolic, Flavonoids, HPLC, diabetic nephropathy

Authors

First Name

Amani MD

Last Name

El-Mesallamy

MiddleName

-

Affiliation

Department of Organic Chemistry, Faculty of Science, Zagazig University, Zagazig, Egypt

Email

-

City

-

Orcid

-

First Name

Sahar

Last Name

Hussein

MiddleName

-

Affiliation

Department of Phytochemistry and Plant Systematics ,National Research Center , Egypt

Email

drsahar90@yahoo.com

City

Cairo

Orcid

0000-0002-6305-508X

First Name

Abdel Aziz M

Last Name

Hussein

MiddleName

-

Affiliation

Department of Physiology, Faculty of Medicine, Mansoura University, Mansoura, Egypt

Email

-

City

-

Orcid

-

First Name

Seham A

Last Name

Mahmoud

MiddleName

-

Affiliation

Department of Organic Chemistry, Faculty of Science, Zagazig University, Zagazig, Egypt

Email

-

City

-

Orcid

-

First Name

Khalid M.

Last Name

El-Azab

MiddleName

-

Affiliation

Department of Biology, Faculty of Science, JazanUniversity, Jazan, Saudi Arabia

Email

-

City

-

Orcid

-

Volume

61

Article Issue

4

Related Issue

1586

Issue Date

2018-08-01

Receive Date

2018-04-15

Publish Date

2018-08-01

Page Start

609

Page End

615

Print ISSN

0449-2285

Online ISSN

2357-0245

Article File

EJCHEM_Volume 61_Issue 4_Pages 609-615.pdf

PDF . 1.2MB

Link

https://ejchem.journals.ekb.eg/article_7331.html

Detail API

https://ejchem.journals.ekb.eg/service?article_code=7331

Order

4

Type

Original Article

Type Code

297

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry

Publication Link

https://ejchem.journals.ekb.eg/

MainTitle

-

Details

Type

Article

Created At

22 Jan 2023