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Cyanoacetyl urea in heterocyclic synthesis part V: Facile synthesis of poly-functionalized pyrimdines via different behaviors of its free urea amino group

Article

Last updated: 01 Jan 2025

OverviewSimilar Items

Subjects

-

Tags

Organic chemistry

Abstract

The poly-functional precursor, cyano-acetyl urea, could be utilized in the synthesis of various pyrimidens utilizing its benzothiazole derivative 1. The free amino group in 1 undergoes different chemical behavior according to the reaction conditions to afford pyrimidines 3,4,5,6,7a,b and 9a,b, respectively.

DOI

10.21608/ejchem.2018.2297.1190

Keywords

1, 3-Benzothiazole, Pyrimidine, Cyanoacetyl urea, small molecules

Authors

First Name

Hoda

Last Name

Othman

MiddleName

Sabry

Affiliation

Green Chemistry department, National research centre

Email

hoda_sabry2@yahoo.com

City

-

Orcid

-

First Name

Maher

Last Name

Al-Hashash

MiddleName

-

Affiliation

Chemistry Department, Faculty of Science, Ain-shams University

Email

maher_elhashash@sci.asu.edu.eg

City

-

Orcid

-

First Name

Galal

Last Name

Nawwar

MiddleName

Abd El-Moein

Affiliation

Green chemistry department, National Research Centre

Email

gnawwar@yahoo.com

City

-

Orcid

-

Volume

61

Article Issue

1

Related Issue

936

Issue Date

2018-02-01

Receive Date

2017-12-12

Publish Date

2018-02-01

Page Start

207

Page End

212

Print ISSN

0449-2285

Online ISSN

2357-0245

Article File

EJCHEM_Volume 61_Issue 1_Pages 207-212.pdf

PDF . 473.8kB

Link

https://ejchem.journals.ekb.eg/article_5093.html

Detail API

https://ejchem.journals.ekb.eg/service?article_code=5093

Order

19

Type

Original Article

Type Code

297

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry

Publication Link

https://ejchem.journals.ekb.eg/

MainTitle

Cyanoacetyl urea in heterocyclic synthesis part V: Facile synthesis of poly-functionalized pyrimdines via different behaviors of its free urea amino group

Details

Type

Article

Created At

22 Jan 2023