A series of borophosphate glasses doped individually with few antibacterial oxides; CeO2, ZnO and CuO were prepared by melt quenching technique. The structure and bioactivity of the prepared samples were analyzed through FTIR spectral technique and corrosion behavior before and after immersion for 2 weeks in simulated body fluid (SBF) under static condition. Microstructure of the glass was examined using SEM to confirm the bioactivity of glass through the formation of calcium phosphate (CaP) layer on the surface. FTIR spectra of the glass after immersion in SBF show characteristic peaks of calcium phosphate. Weight loss% display a difference in solubility in the SBF solution in relation to the antibacterial oxide added. SEM results show clear nodular microcrystalline calcium phosphate. The prepared glasses revealed effect against some microbes and bacteria. It was established that the addition of the antibacterial oxides had a positive effect on the glass bioactivity and may find a part in biomedical applications.