work aims to synthesis of fast green biogenic silver nanoparticles (AgNPs) using the ethanolic extracts of three Terminalia spices, namely, T. catapa (T.C), T. bellarica (T.B) and T. mellurie (T.M). AgNPs formed was affirmed by using UV–visible spectrophotometer with the characteristic SPR (Surface Plasmon Resonance) band at 424-430nm and by using FT-IR (Fourier transform infrared spectroscopy) and TEM (transmission electron microscopy). Quantification of carbohydrates, total phenolic compounds, flavonoids, and protein contents of these extracts were appraised since these constituents have effective dual roles for AgNPs synthesis. That is, they reduce Ag+ ions to Ag˚ nanoparticles and thereafter they stabilize these particles. GC/MS analyses of these extracts were also done. The cotton fabrics treated with the synthesized AgNPs showed good antimicrobial and anti-inflammatory activities toward both Gram-positive (S. aureus ATCC 25923) and Gram-negative (E. coli ATCC 25922) bacteria.