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1544

Synthesis and Antitumor Activity Evaluation of New 2-(4-aminophenyl) benzothiazole/oxazole/imidazole Derivatives

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Last updated: 22 Jan 2023

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Abstract

A NEW series of 2-(4-aminophenyl)benzothiazole and related structure compounds, bearing thiocyanate, thiol in the 3'postion as well as new condensed benzothiazoles and related structure compounds having thiazolones ,tetrazole, oxadiazole have been synthesized . All the newly synthesized compounds were screened for their anti-tumor activities. The results revealed promising effects against most of the cancer cell lines.

DOI

10.21608/ejchem.2016.1544

Keywords

2-(4 aminophenyl) benzothiazole/ benzoxazole/ benzimidazole, Tetrazole, Oxadiazole, thiazole, Oxobutanoate, Tolyiformamidine, Chlorophenyl-formamidine, anticancer agent

Volume

59

Article Issue

6

Related Issue

326

Issue Date

2016-12-01

Receive Date

2016-10-16

Publish Date

2016-12-31

Page Start

967

Page End

984

Print ISSN

0449-2285

Online ISSN

2357-0245

Link

https://ejchem.journals.ekb.eg/article_1544.html

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https://ejchem.journals.ekb.eg/service?article_code=1544

Order

3

Type Code

292

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry

Publication Link

https://ejchem.journals.ekb.eg/

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Article

Created At

22 Jan 2023