Synthesis of Fused Heterocyclic Compounds Derived from 2-Phenyl[1,5]benzothiazepin-4(5H)-One - Egyptian Knowledge Bank

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Synthesis of Fused Heterocyclic Compounds Derived from 2-Phenyl[1,5]benzothiazepin-4(5H)-One

Article

Last updated: 01 Jan 2025

Subjects

Abstract

2-PHENYL[1,5]benzothiazepin-4(5H)-one (1) was reacted with arylidenenitriles, a mixture of carbon disulphide or phenyliso-thiocyanate and active nitriles to give pyrano-, pyrido-, thiopyrano-, 1,2-dithiolo[3,4-e]-; 1,3-dithiolo[4,5-e] [1,5] benzothiazepines, benzothi-azepino-[6,5-c] [1,8] naphthyridine and oxathieno [1, 5] benzothiazepines (2 –11), respectively. Treatment of compound 1 with a mixture of sulphur and phenyl isothiocyanate or 2-amino-1,1,3- tricyano-2-aminopropene gave 1,3-dithieno [4,5-e]- and thieno [3,2-e]- [1,5] benzothiazepines (12, 13), respectively.

DOI

10.21608/ejchem.2011.1400

Keywords

1, 5-Benzothiazepin-4(5H)-one, Naphthyridines and Thieno [3, 2-e] benzothiazepines

Volume

Article Issue

Related Issue

305

Issue Date

2012-06-01

Receive Date

2011-05-17

Publish Date

2011-06-30

Page Start

349

Page End

359

Print ISSN

0449-2285

Online ISSN

2357-0245

Article File

EJCHEM_Volume 54_Issue 3_Pages 349-359.pdf

PDF . 270.5kB

Link

https://ejchem.journals.ekb.eg/article_1400.html

Detail API

https://ejchem.journals.ekb.eg/service?article_code=1400

Order

Type Code

292

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry

Publication Link

https://ejchem.journals.ekb.eg/

MainTitle