Utility of p-Acetamidobenzoyl Prop-2-enoic Acid in the Synthesis of New α-Amino Acids and Using Them as Building Blocks in Heterocyclic Synthesis - Egyptian Knowledge Bank

1396

Utility of p-Acetamidobenzoyl Prop-2-enoic Acid in the Synthesis of New α-Amino Acids and Using Them as Building Blocks in Heterocyclic Synthesis

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Last updated: 01 Jan 2025

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Abstract

THE PRESENT work deals with the generation and synthesis of different unnatural amino acid derivatives via treatment of 3-(4-acetamidobenzoyl)-prop-2-enoic acid with 5-aryl-2- amino 1, 3, 4 thiadiazole, 3, 5-dimethyl pyrazole and barbituric acid to afford the product of conjugate addition acids (1) respectively. Additionally, the adduct 1 are used as key starting materials to synthesize some heterocycles include pyridazene , furanone and oxazine derivatives. The antimicrobial screening of some of the synthesized compounds was done using the agar diffusion assay

DOI

10.21608/ejchem.2011.1396

Keywords

3-Acetamidobenzoyl prop-2-enoic acid, Pyrazole thiadiazole, Phthalimide, Barbituric acid, furanone, Pyridazine and Oxazine

Volume

Article Issue

Related Issue

305

Issue Date

2012-06-01

Receive Date

2011-01-04

Publish Date

2011-06-30

Page Start

299

Page End

312

Print ISSN

0449-2285

Online ISSN

2357-0245

Article File

EJCHEM_Volume 54_Issue 3_Pages 299-312.pdf

PDF . 426.0kB

Link

https://ejchem.journals.ekb.eg/article_1396.html

Detail API

https://ejchem.journals.ekb.eg/service?article_code=1396

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Type Code

292

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry

Publication Link

https://ejchem.journals.ekb.eg/

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