1.4-Arylation of β-(4-acetylaminobenzoyl)acrylic Acid with Activated Aromatic Hydrocarbons under Friedel-Crafts Conditions and Some Studies with the Products - Egyptian Knowledge Bank

1380

1.4-Arylation of β-(4-acetylaminobenzoyl)acrylic Acid with Activated Aromatic Hydrocarbons under Friedel-Crafts Conditions and Some Studies with the Products

Article

Last updated: 22 Jan 2023

Overview Similar Items

Subjects

Abstract

THE BEHAVIUOR of 3-(4-acetylaminobenzoyl) prop-2-enoic acid 1 with m-xylene and\or p-xylene under Friedel-Craft,s reaction conditions yielded 2- ( 2,4-Dimethyl and/or 2,5-dimethyl ) phenyl-3-(4-acetylaminobenzoyl)propanoic acids (2a,b) and thia-Micheal of acid 1 afforded 2- phenyl sulfanyl-3-(4-acetylamino benzoyl propanoic acid (3). Interaction of acids 2,3 with N2H4 , AC2O, NH2OH.HCl and PhNHNH2, yielded pyridazinone 4 , Furanone 5 1, 2oxazine 6 and 2-phenyl pyridazinone derivatives, respectively. Treatment of pyridazinone 4 with different interesting alkyl halides afforded the pyridazine derivatives 8 .

DOI

10.21608/ejchem.2011.1380

Keywords

3-Aroyl prop-2-enoic acid. Pyridazinone. Furanone, oxazinone and Alkyl pyridazine

Volume

Article Issue

Related Issue

303

Issue Date

2012-02-01

Receive Date

2011-01-04

Publish Date

2011-02-28

Page Start

Page End

Print ISSN

0449-2285

Online ISSN

2357-0245

Article File

EJCHEM_Volume 54_Issue 1_Pages 69-79.pdf

PDF . 476.6kB

Link

https://ejchem.journals.ekb.eg/article_1380.html

Detail API

https://ejchem.journals.ekb.eg/service?article_code=1380

Order

Type Code

292

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry

Publication Link

https://ejchem.journals.ekb.eg/

MainTitle

Details

Type