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1377

Behaviour of 4,6-Diaryl-2(1H) pyrimidine-2-thiones Towards Some Electrophiles and Nucleophiles

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Last updated: 22 Jan 2023

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Abstract

 4,6-DIARYl-1,2-dihydro-2(1H)-pyrimidine-2-thiones (1a,b) were ….used for the synthesis of several new pyrimidine derivatives. They were further subjected to hetero ring anellation affording isoxazolo [4,5-d] thiazolo [2,3-a] pyrimidine (5,6) and isoxazolo [4,5-d] thiazino [2,3-a] pyrimidines (11,12) . Biological evaluation of some of the prepared compounds revealed promising antimicrobial activity.

DOI

10.21608/ejchem.2011.1377

Keywords

Pyrimidinethione, Pyrimidothiazine, Thiazolopyrimidine and Antimicrobial activity

Volume

54

Article Issue

1

Related Issue

303

Issue Date

2012-02-01

Receive Date

2010-07-13

Publish Date

2011-02-28

Page Start

17

Page End

34

Print ISSN

0449-2285

Online ISSN

2357-0245

Link

https://ejchem.journals.ekb.eg/article_1377.html

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https://ejchem.journals.ekb.eg/service?article_code=1377

Order

2

Type Code

292

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry

Publication Link

https://ejchem.journals.ekb.eg/

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Article

Created At

22 Jan 2023