Novel Synthesis of Fused Pyrazolopyrimidines and C-Nucleosides of Thienopyrimidone with Expected Antimicrobial Activity - Egyptian Knowledge Bank

1247

Novel Synthesis of Fused Pyrazolopyrimidines and C-Nucleosides of Thienopyrimidone with Expected Antimicrobial Activity

Article

Last updated: 22 Jan 2023

Subjects

Abstract

STARTING from thienopyrimidine hydrazine derivatives (1a,d) and (2b,c) a series of pyrazolopyrimidine derivatives has been synthesized. Also, some acyclic and cyclic C- nucleosides of thienopyrimidone (7-10) were prepared by treating compound 1a with aldoses. The prepared products showed antimicrobial activity. Structures of the new compounds were elucidated on the basis of their elemental analyses and spectral data.

DOI

10.21608/ejchem.2010.1247

Keywords

pyrazolopyrimidine, C-Nucleosides, NMR spectra, Mass spectra, Antibacterial and Antifungal Activities

Volume

Article Issue

Related Issue

291

Issue Date

2010-08-01

Receive Date

2010-07-20

Publish Date

2010-08-30

Page Start

527

Page End

540

Print ISSN

0449-2285

Online ISSN

2357-0245

Article File

EJCHEM_Volume 53_Issue 4_Pages 527-540.pdf

PDF . 459.1kB

Link

https://ejchem.journals.ekb.eg/article_1247.html

Detail API

https://ejchem.journals.ekb.eg/service?article_code=1247

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Type Code

292

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry

Publication Link

https://ejchem.journals.ekb.eg/

MainTitle

Details

Type