Synthesis of Some New Thieno [2, 3-d] pyrimidines - Egyptian Knowledge Bank

1226

Synthesis of Some New Thieno [2, 3-d] pyrimidines

Article

Last updated: 22 Jan 2023

Subjects

Abstract

4IMINO-3N- (substituted) -5-(thiophen-2-yl) -3,4,dihydro-thieno [2,3-d] pyrimidine-2(1H) (2) was used as precursor for the preparation of some novel 1-(2,3-dihydro-3-methyl-5-(thiophen-2-yl)-2-thioxothieno[2,3-d] pyrimidine – 4 (1H)-ylidene) -3-methyl or phenylthiourea (3a,b) and also for the preparation of 2-Hydrazinyl -3-methyl-5- (thiophen-2-yl)- thieno [2,3-d] pyrimidin-4(3H-imine) (5) which was reacted with methyl and phenylisothiocyanat at room temp. to give compounds 6a,b. Also, 5 was reacted with methylisothiocyanate, and / or formic acid to give the triazolopyrimidines 7 and 8. Also, 5 was reacted with nitrous acid to give the 2-azido thienopyrimidine 9.

DOI

10.21608/ejchem.2010.1226

Keywords

THIENOPYRIMIDINE, Triazolopyrimidines and Azido thienopyrimidine

Volume

Article Issue

Related Issue

290

Issue Date

2010-06-01

Receive Date

2010-03-29

Publish Date

2010-06-30

Page Start

359

Page End

366

Print ISSN

0449-2285

Online ISSN

2357-0245

Article File

EJCHEM_Volume 53_Issue 3_Pages 359-366.pdf

PDF . 378.9kB

Link

https://ejchem.journals.ekb.eg/article_1226.html

Detail API

https://ejchem.journals.ekb.eg/service?article_code=1226

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Type Code

292

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry

Publication Link

https://ejchem.journals.ekb.eg/

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Details

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